Ozen H A, Basar I, Erbas B, Ozen S, Ergen A, Balkanci F, Bakkaloğlu M, Saatci U, Bakkaloğlu A
University of Hacettepe, Ankara, Turkey.
Eur Urol. 1990;17(1):47-50. doi: 10.1159/000463999.
32 children admitted to Hacettepe University Hospital for surgical treatment of vesicoureteral reflux (VUR) between 1987 and 1988 were included in this prospective double-blind study. All patients underwent intravenous urography (IVU), voiding cystouretrography and 99mTc DMSA renal scanning. The sensitivity and specificity of the DMSA scan and IVU for detecting renal scarring were investigated. With regard to the presence of renal scarring, the sensitivity and specificity of IVU and DMSA were not found to be statistically different. But when the scars were scored, DMSA was found to have a higher scoring index compared to IVU. In patients who were candidates for surgical management of VUR, renal scars could be detected both by IVU and DMSA scan but, for the follow-up, the DMSA scan was found to be the investigation of choice.
1987年至1988年间,32名因膀胱输尿管反流(VUR)入住哈杰泰佩大学医院接受手术治疗的儿童被纳入这项前瞻性双盲研究。所有患者均接受了静脉肾盂造影(IVU)、排尿性膀胱尿道造影和99mTc二巯基丁二酸(DMSA)肾扫描。研究了DMSA扫描和IVU检测肾瘢痕的敏感性和特异性。关于肾瘢痕的存在,未发现IVU和DMSA的敏感性和特异性有统计学差异。但在对瘢痕进行评分时,发现DMSA的评分指数高于IVU。在VUR手术治疗候选患者中,IVU和DMSA扫描均可检测到肾瘢痕,但在随访中,发现DMSA扫描是首选的检查方法。