University Hospital Heidelberg, Department of Diagnostic and Interventional Radiology, Im Neuenheimer Feld 110, 69120 Heidelberg, Germany.
Eur J Vasc Endovasc Surg. 2011 Sep;42(3):324-31. doi: 10.1016/j.ejvs.2011.04.019. Epub 2011 May 13.
The study aimed to test whether reliability and inter-observer variability of preoperative measurements for thoracic endovascular aortic repair (TEVAR) among non-experts are improved by semiautomatic centerline analysis compared with manual assessment.
Preoperative computed tomography (CT) angiographies of 30 patients with thoracic aortic disease (mean age 66.8 ± 11.6 years, 23 men) were retrospectively analysed in randomised order by one blinded vascular expert (reference standard) and three blinded non-expert readers. Aortic diameters were measured at four positions relevant to TEVAR using three measurement techniques (manual axial slices, manual multiplanar reformations (MPRs) and semiautomatic centerline analysis). Length measurements were performed using centerline analysis. Reliability was calculated as absolute measurement deviation (AMD) from reference standard and inter-observer variability as coefficient of variance (CV) among non-expert readers.
For axial, MPR and centerline techniques, mean AMD was 7.3 ± 7.7%, 6.7 ± 4.5% and 4.7 ± 4.8% and mean CV was 5.2 ± 4.2%, 5.8 ± 4.8% and 3.9 ± 5.4%. Both AMD and CV were significantly lower for centerline analysis compared with axial technique (p = 0.001/0.042) and MPR (p = 0.009/0.003). AMD and CV for length measurements by centerline analysis were 3.2 ± 2.8% and 2.6 ± 2.4%, respectively. Centerline analysis was significantly faster than MPR (p < 0.001).
Semiautomatic centerline analysis provides the most reliable and least variable diameter and length measurements among non-experts in candidates for TEVAR.
本研究旨在测试在非专家中,与手动评估相比,半自动中心线分析是否可以提高胸主动脉腔内修复术(TEVAR)术前测量的可靠性和观察者间变异性。
回顾性分析了 30 例胸主动脉疾病患者(平均年龄 66.8±11.6 岁,23 名男性)的术前计算机断层血管造影(CTA)。由一名盲法血管专家(参考标准)和三名盲法非专家读者以随机顺序进行分析。使用三种测量技术(手动轴向切片、手动多平面重建(MPR)和半自动中心线分析)在与 TEVAR 相关的四个位置测量主动脉直径。使用中心线分析进行长度测量。可靠性计算为与参考标准的绝对测量偏差(AMD),观察者间变异性计算为非专家读者之间的变异系数(CV)。
对于轴向、MPR 和中心线技术,平均 AMD 分别为 7.3±7.7%、6.7±4.5%和 4.7±4.8%,平均 CV 分别为 5.2±4.2%、5.8±4.8%和 3.9±5.4%。与轴向技术(p=0.001/0.042)和 MPR(p=0.009/0.003)相比,中心线分析的 AMD 和 CV 均显著降低。中心线分析的长度测量的 AMD 和 CV 分别为 3.2±2.8%和 2.6±2.4%。与 MPR 相比,中心线分析显著更快(p<0.001)。
在 TEVAR 候选者中,半自动中心线分析为非专家提供了最可靠和最具可变性的直径和长度测量。