Kopp L, Obruba P, Edelmann K, Procházka B, Blšťáková K, Celko A M
Traumacentrum, Masarykova nemocnice, Ústí nad Labem.
Acta Chir Orthop Traumatol Cech. 2011;78(2):156-60.
We aimed to determine the incidence of pressure sores and their effect on survival in patients older than 70 years who underwent surgery for hip fracture, and to identify the factors which were associated with an increased risk of pressure sores.
The group comprised 269 patients (219 women and 50 men) older than 70 years who underwent surgery for proximal femoral fractures in the Trauma center between January 2003 and June 2005. Follow-up ranged from 12 to 18 months. In a prospective study we assessed relevant medical history, demographic and clinical data, pre-, intra-, and post-operative factors and the presence, location and depth of pressure sores. Statistical significance at a 5 % level of probability was determined by testing null hypotheses for qualitative and quantitative variables, using multivariate analysis adjusted for selected baseline characteristics.
The average age of the patient group was 81 years (range, 70-99). Pressure ulcers developed in 92 patients (34.2 %); their presence in the post-operative period significantly reduced patient survival (p=0.037). In terms of location, pressure ulcers in the calcaneal region had a more significant effect on patient mortality (p=0.011) than those in the sacral region (p=0.130). Age was not significantly associated with pressure ulcer development (p=0.547), in contrast to male gender (p=0.007). A lower mobility score before injury was a significant risk factor (p=0.007). Co-morbidities adjusted for age and gender had a significant effect (p=0.003). The factors that did not significantly increase the risk of pressure ulcers were as follows: the patient's living environment before injury (p=0.113), AO type of fracture (p=0.653), type of anaesthesia (p=0.702), surgical procedure used (p=0.946), morbidity before injury (p=0.267) and time to surgery (p=0.180). The presence of acute complications was of boundary significance (p=0.083). DISCUSSION The study included only the patients with proximal femoral fractures who underwent surgery. It was the authors' view that, by excluding conservatively treated patients, a more homogenous group was achieved. There is only sparse information in the literature concerning the effect of pressure ulcers on reduced patient survival, and the significance of pressure ulcer location has not been evaluated at all. Similarly, the effect of pre-morbidity on pressure ulcer development has not been reported in any of the studies available. In contrast to other studies, the authors did not find age to be a risk factor for increased ulcer development. They believe that the quality and quantity of the input data (prospective data collection, large sample size, long follow-up) guarantee the validity of the results obtained in this study. The incidence of pressure sores is in agreement with the results of relevant studies involving large numbers of patients and prolonged follow-up.
In patients older than 70 years undergoing surgery for hip fracture, the development of pressure ulcers had a significant effect on reduced survival, with the highest significance for ulcers in the calcaneal region. Factors significantly increasing the risk of ulcer development were male gender, morbidity before injury and pre-existing chronic complications. The presence of acute complications was of boundary significance. The study did not show any significant effect of age, pre-morbidities, time to surgery, patient's living environment before injury, fracture type, type of anaesthesia or surgical procedure used on the incidence of pressure ulcers.
我们旨在确定70岁以上接受髋部骨折手术患者的压疮发生率及其对生存的影响,并确定与压疮风险增加相关的因素。
该组包括2003年1月至2005年6月间在创伤中心接受股骨近端骨折手术的269例70岁以上患者(219名女性和50名男性)。随访时间为12至18个月。在一项前瞻性研究中,我们评估了相关病史、人口统计学和临床数据、术前、术中和术后因素以及压疮的存在、位置和深度。通过对定性和定量变量的零假设进行检验,并使用针对选定基线特征进行调整的多变量分析,确定5%概率水平的统计学显著性。
患者组的平均年龄为81岁(范围70 - 99岁)。92例患者(34.2%)发生了压疮;术后发生压疮显著降低了患者的生存率(p = 0.037)。就位置而言,跟骨区域的压疮对患者死亡率的影响(p = 0.011)比骶骨区域的压疮更显著(p = 0.130)。年龄与压疮发生无显著相关性(p = 0.547),而男性性别则有显著相关性(p = 0.007)。受伤前活动能力评分较低是一个显著的危险因素(p = 0.007)。经年龄和性别调整后的合并症有显著影响(p = 0.003)。未显著增加压疮风险的因素如下:受伤前患者的生活环境(p = 0.113)、AO骨折类型(p = 0.653)、麻醉类型(p = 0.702)、所采用的手术方式(p = 0.946)、受伤前的发病率(p = 0.267)和手术时间(p = 0.180)。急性并发症的存在具有临界显著性(p = 0.083)。讨论本研究仅纳入了接受手术的股骨近端骨折患者。作者认为,通过排除保守治疗的患者,得到了一个更同质的组。关于压疮对患者生存率降低的影响,文献中仅有稀少信息,而且压疮位置的意义根本未得到评估。同样,在现有任何研究中均未报道发病前状况对压疮发生的影响。与其他研究不同,作者未发现年龄是溃疡发生增加的危险因素。他们认为输入数据的质量和数量(前瞻性数据收集、大样本量、长时间随访)保证了本研究结果的有效性。压疮发生率与涉及大量患者并进行长期随访的相关研究结果一致。
在70岁以上接受髋部骨折手术的患者中,压疮的发生对生存率降低有显著影响,跟骨区域的溃疡影响最为显著。显著增加溃疡发生风险的因素为男性性别、受伤前的发病率和既往慢性并发症。急性并发症的存在具有临界显著性。该研究未显示年龄、发病前状况、手术时间、受伤前患者的生活环境、骨折类型、麻醉类型或所采用的手术方式对压疮发生率有任何显著影响。