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STORM:用于检验亲缘关系和交配模式假设的软件。

STORM: software for testing hypotheses of relatedness and mating patterns.

机构信息

Natural Resources DNA Profiling and Forensic Centre, DNA Building, Trent University, 2140 East Bank Drive, Peterborough, ON, Canada K9J 7B8.

出版信息

Mol Ecol Resour. 2008 Nov;8(6):1263-6. doi: 10.1111/j.1755-0998.2008.02358.x.

Abstract

Storm is a software package that allows users to test a variety of hypotheses regarding patterns of relatedness and patterns of mate choice and/or mate compatibility within a population. These functions are based on four main calculations that can be conducted either independently or in the hypothesis-testing framework: internal relatedness; homozygosity by loci; pairwise relatedness; and a new metric called allele inheritance, which calculates the proportion of loci at which an offspring inherits a paternal allele different from that inherited from its mother. STORM allows users to test four hypotheses based on these calculations and Monte Carlo simulations: (i) are individuals within observed associations or groupings more/less related than expected; (ii) do observed offspring have more/less genetic variability (based on internal relatedness or homozygosity by loci) than expected from the gene pool; (iii) are observed mating pairs more/less related than expected if mating is random with respect to relatedness; and (iv) do observed offspring inherit paternal alleles different from those inherited from the mother more/less often than expected based on Mendelian inheritance.

摘要

Storm 是一款软件包,允许用户针对群体内的亲缘关系模式和配偶选择/配偶兼容性模式检验各种假设。这些功能基于四项主要的计算,可以独立进行,也可以在假设检验框架中进行:内部相关性;基因座同型性;成对相关性;以及一种称为等位基因遗传的新度量,该度量计算后代在哪些基因座上继承了与从其母亲继承的不同的父等位基因。STORM 允许用户根据这些计算和蒙特卡罗模拟检验四个假设:(i) 观察到的关联或分组内的个体是否比预期的更相关/不相关;(ii) 观察到的后代是否比预期从基因库中具有更多/更少的遗传变异性(基于内部相关性或基因座同型性);(iii) 如果配偶选择与相关性随机相关,观察到的交配对是否比预期的更相关/不相关;以及 (iv) 观察到的后代继承来自父亲的不同于来自母亲的等位基因的频率是否比基于孟德尔遗传的预期更高/更低。

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