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黏膜移植治疗 Stevens-Johnson 综合征后联带症:一例报告。

Mucous membrane grafting for the post-Steven-Johnson syndrome symblepharon: a case report.

机构信息

Sri Sankaradeva Nethralaya, Beltola, Guwahati - 781 028, Assam, India.

出版信息

Indian J Ophthalmol. 2011 May-Jun;59(3):231-3. doi: 10.4103/0301-4738.81039.

Abstract

An 18-year-old woman was referred with late sequelae of chloroquine-induced Steven-Johnson syndrome. At the time of presentation, the symblepharon was involving the upper lids to almost the whole of the cornea, and part of the lower bulbar conjunctiva with the lower lid bilaterally. Other ocular examinations were not possible due to the symblepharon. B-scan ultrasonography revealed acoustically clear vitreous, normal chorioretinal thickness, and normal optic nerve head, with an attached retina. Conjunctivo-corneal adhesion released by superficial lamellar dissection of the cornea. Ocular surface reconstruction was carried out with a buccal mucous membrane. A bandage contact lens was placed over the cornea followed by the symblepharon ring to prevent further adhesion. The mucosal graft was well taken up along with corneal re-epithelization. Best corrected visual acuity of 20/120 in both sides after 1 month and 20/80 after 3 months was achieved and maintained till the 2.5-year follow-up.

摘要

一位 18 岁女性因氯喹引起的史蒂文斯-约翰逊综合征后遗症而就诊。就诊时,她的睑球粘连累及上睑,几乎覆盖整个角膜,部分下穹隆球结膜和双侧下睑。由于睑球粘连,其他眼部检查无法进行。B 型超声检查显示玻璃体声影清晰,脉络膜视网膜厚度正常,视神经乳头正常,视网膜附着。通过浅层角膜板层分离松解睑球粘连。用颊黏膜进行眼表重建。在角膜上覆盖绷带式隐形眼镜,然后使用睑球粘连环,以防止再次粘连。黏膜移植物与角膜再上皮化一起被很好地吸收。1 个月后,双眼最佳矫正视力达到 20/120,3 个月后达到 20/80,并在 2.5 年的随访中保持稳定。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92ad/3120246/c62f53146811/IJO-59-231-g001.jpg

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