一名17岁女性，患有与细小病毒感染相关的肝脾T细胞淋巴瘤。
A seventeen-year-old female with hepatosplenic T-cell lymphoma associated with parvoviral infection.
作者信息
Haque Saadiya A, Xiang Ying, Ozdemirli Metin, Shad Aziza, Kallakury Bhaskar
机构信息
Department of Pathology;
出版信息
Pediatr Rep. 2010 Jun 18;2(1):e11. doi: 10.4081/pr.2010.e11.
Hepatosplenic T-cell lymphoma (HSTL) is rare, being derived from cytotoxic T-cells, and manifests as an extranodal systemic lymphoma. We present an unusual case of a seventeen-year-old female, with no significant prior medical history, presenting with a hepatosplenic T-cell lymphoma. The diagnosis was confirmed by histological examination, immunohistochemisty, and flow cytometry. A staging work-up demonstrated bone marrow involvement by HSTL with concomitant intranuclear parvoviral inclusions.
肝脾T细胞淋巴瘤（HSTL）较为罕见，起源于细胞毒性T细胞，表现为结外系统性淋巴瘤。我们报告了一例不寻常的病例，一名17岁女性，既往无重大病史，被诊断为肝脾T细胞淋巴瘤。诊断通过组织学检查、免疫组织化学和流式细胞术得以证实。分期检查显示该肝脾T细胞淋巴瘤累及骨髓，并伴有核内细小病毒包涵体。
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