盲肠炎的危险因素。

Risk factors for typhlitis.

作者信息

Biasoli I, Nucci M, Spector N, Portugal R, Domingues A, Pulcheri W

机构信息

UNIV FED RIO DE JANEIRO,HOSP UNIV CLEMENTINO FRAGA FILHO,SERV HEMATOL,BR-21941590 RIO JANEIRO,BRAZIL.

出版信息

Oncol Rep. 1997 Sep-Oct;4(5):1029-31. doi: 10.3892/or.4.5.1029.

DOI:10.3892/or.4.5.1029

PMID:21590189

Abstract

A case-control study was undertaken to identify risk factors for typhlitis in patients with hematological malignancies. A data base file with a total of 410 episodes of fever and neutropenia in patients cared for between May 1987 and 1996 was reviewed. Typhlitis was defined as a symptom complex of fever, intense abdominal pain and tenderness in the presence of neutropenia. Five cases of typhlitis were identified. Three controls for every patient were randomly selected from the same cohort. Diarrhea and jaundice were more frequent in patients than in controls (p=0.03). The presence of mucositis, prolonged duration of profound neutropenia and idarubicin treatment proved to be risk factors for typhlitis.

摘要

开展了一项病例对照研究，以确定血液系统恶性肿瘤患者发生盲肠炎的危险因素。回顾了一个数据库文件，其中包含1987年5月至1996年期间接受治疗的患者共410次发热和中性粒细胞减少发作情况。盲肠炎被定义为在中性粒细胞减少的情况下出现发热、剧烈腹痛和压痛的症状复合体。确定了5例盲肠炎病例。从同一队列中为每名患者随机选取3名对照。患者中腹泻和黄疸比对照更常见（p=0.03）。黏膜炎的存在、严重中性粒细胞减少的持续时间延长和伊达比星治疗被证明是盲肠炎的危险因素。