Nakahara Yoshiro, Okamura Tatsuru, Okuma Yusuke, Takagi Yusuke, Miyamoto Shingo, Shimokawa Tsuneo, Hosomi Yukio, Iguchi Mari, Hishima Tsunekazu, Shibuya Masahiko
Division of Respiratory Disease, Department of Internal Medicine, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital.
Nihon Kokyuki Gakkai Zasshi. 2011 Apr;49(4):321-6.
An asymptomatic 77-year-old woman was referred in 2000 because multiple nodular shadows were found on chest X-ray films on a medical checkup. Chest computed tomography (CT) showed bilateral multiple ground-glass opacities and ill-defined nodules. A transbronchial lung biopsy was performed via bronchoscopy, but the specimens did not yield any specific findings. She was then monitored without therapy as an outpatient. In November 2005, chest CT imaging showed that the size and density of the ground-glass opacities and nodules had increased. In January, 2006 video-assisted thoracic surgery (VATS) was performed to obtain a definitive diagnosis. Based on histological and immunohistochemical examinations, primary pulmonary mucosa-associated lymphoid tissue (MALT) lymphoma was diagnosed. She has been followed up without any additional treatment since.
Multiple ground glass opacities and nodules are rare chest CT findings in pulmonary MALT lymphoma.
2000年，一名77岁无症状女性因体检时胸部X光片发现多个结节状阴影而前来就诊。胸部计算机断层扫描（CT）显示双侧多个磨玻璃影和边界不清的结节。通过支气管镜进行了经支气管肺活检，但标本未发现任何特异性结果。随后她作为门诊患者接受观察，未进行治疗。2005年11月，胸部CT成像显示磨玻璃影和结节的大小及密度增加。2006年1月，进行了电视辅助胸腔镜手术（VATS）以明确诊断。根据组织学和免疫组化检查，诊断为原发性肺黏膜相关淋巴组织（MALT）淋巴瘤。此后一直对她进行随访，未进行任何额外治疗。
多发性磨玻璃影和结节是肺MALT淋巴瘤罕见的胸部CT表现。
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