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[帕纳约托普洛斯综合征:学业困难与行为障碍]

[Panayiotopoulos syndrome: academic difficulties and behavioural disorders].

作者信息

Pérez-Villena Ana, López-Marín Laura, Cantarín-Extremera Verónica, Leon-Gonzalez Miguelina, Fournier-Del Castillo Concepción, Ruiz-Falcó M Luz

机构信息

Servicio de Neuropediatría, Hospital Infantil Universitario Niño Jesús, Madrid, Spain.

出版信息

Rev Neurol. 2011 Jun 16;52(12):705-12.

Abstract

INTRODUCTION

Panayiotopoulos syndrome (PS) is one of the benign epilepsies found in childhood. Some papers have shown that patients can present behavioural disorders and learning difficulties.

AIMS

To review patients diagnosed with PS in our hospital and to check whether they display evidence of such disorders and if there is any specific feature that allows high-risk patients to be identified.

PATIENTS AND METHODS

A retrospective review of the medical records of patients diagnosed with PS was carried out. An electroencephalogram (EEG) or video-EEG-polygraph recordings were performed on all patients during sleep. The Weschler Intelligence Scale for Children was used to evaluate intelligence.

RESULTS

Data were collected for 33 patients, 17 of whom were children. The mean age at onset was 3.2 years and the follow-up was 4.9 years (range: 1-12 years). Irritative EEG phenomena were detected in the occipital (67.7%), temporal (45.2%) or parietal regions (22.5%) in 31 patients. Furthermore, 72.7% of patients presented more than two seizures. Twenty-three patients required treatment with antiepileptic drugs. Two patients were diagnosed with attention deficit hyperactivity disorder. Additionally, 30.3% reported dispersed attention and 27.3% had an impulsive character. It was found that 51.1% had a good level of academic achievement, in 26.5% it was regular and in 17.6% poor. A total of 39.4% needed assistance in the form of after-school classes. The level of intelligence was evaluated in 11 patients.

CONCLUSION

PS is a condition with a good prognosis, but seems to be associated to learning and behavioural disorders.

摘要

引言

潘纳约托普洛斯综合征(PS)是儿童期发现的良性癫痫之一。一些论文表明,患者可能出现行为障碍和学习困难。

目的

回顾我院诊断为PS的患者,检查他们是否有此类障碍的证据,以及是否有任何特定特征可用于识别高危患者。

患者与方法

对诊断为PS的患者病历进行回顾性研究。所有患者在睡眠期间均进行了脑电图(EEG)或视频脑电图多导记录。使用韦氏儿童智力量表评估智力。

结果

收集了33例患者的数据,其中17例为儿童。平均发病年龄为3.2岁,随访时间为4.9年(范围:1 - 12年)。31例患者在枕叶(67.7%)、颞叶(45.2%)或顶叶区域(22.5%)检测到刺激性脑电图现象。此外,72.7%的患者发作超过两次。23例患者需要使用抗癫痫药物治疗。2例患者被诊断为注意力缺陷多动障碍。此外,30.3%的患者报告注意力分散,27.3%的患者性格冲动。发现51.1%的患者学业成绩良好,26.5%的患者成绩一般,17.6%的患者成绩较差。共有39.4%的患者需要课外辅导形式的帮助。对11例患者进行了智力水平评估。

结论

PS预后良好,但似乎与学习和行为障碍有关。

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