Broussard David, Donaldson Emilie, Falterman Jason, Bates Michael
Department of Anesthesiology, Ochsner Clinic Foundation, New Orleans, LA.
Ochsner J. 2011 Spring;11(1):70-7.
From October 2008 to June 2010, a total of 42 patients had the HeartMate II left ventricular assist device inserted surgically at Ochsner Medical Center in New Orleans, LA. A retrospective electronic record review was conducted on this series of patients to analyze elements of perioperative anesthetic care, including general anesthetic care, echocardiographic considerations, and blood product usage. Etomidate was used to induce anesthesia for 34 of 42 patients (81%) in this series, with an average dose of 16.5 mg (±6 mg). The average intraoperative fentanyl dose was 1,318 µg (±631 µg). On average, patients were extubated 91 hours (±72 hours) after arrival to the intensive care unit and left on day 9 (±5 days). The average left ventricular ejection fraction of the patients in this series was 13% (±5%). Sixteen patients were evaluated as having severe right-heart dysfunction preoperatively. Two of 42 patients required surgical closure of echocardiographically identified patent foramen ovale. Twelve of 42 patients underwent surgical correction of tricuspid regurgitation. On average, 3 units (±2.6 units) of fresh frozen plasma were transfused intraoperatively and 10 units postoperatively. Intraoperative red blood cell usage averaged 1.1 units (maximum, 7 units), with an average 9.3 units administered in the first 48 hours postoperatively.
2008年10月至2010年6月,共有42例患者在路易斯安那州新奥尔良市的奥施纳医疗中心接受了HeartMate II左心室辅助装置的外科植入手术。对这组患者进行了回顾性电子病历审查,以分析围手术期麻醉护理的要素,包括全身麻醉护理、超声心动图相关考虑因素以及血液制品的使用情况。在该组42例患者中,有34例(81%)使用依托咪酯诱导麻醉,平均剂量为16.5毫克(±6毫克)。术中芬太尼平均剂量为1318微克(±631微克)。患者平均在进入重症监护病房91小时(±72小时)后拔管,并于第9天(±5天)出院。该组患者的平均左心室射血分数为13%(±5%)。16例患者术前被评估为患有严重的右心功能不全。42例患者中有2例需要对经超声心动图确定的卵圆孔未闭进行手术闭合。42例患者中有12例接受了三尖瓣反流的外科矫正。术中平均输注3单位(±2.6单位)新鲜冰冻血浆,术后输注10单位。术中红细胞平均用量为1.1单位(最大用量为7单位),术后48小时内平均输注9.3单位。