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[鼻窦及相邻颅底良性纤维骨性病变的外科治疗]

[Surgical management of sinonasal and adjacent skull base benign fibro-osseous lesions].

作者信息

Guo Jinbao, Zhang Weitian, Yin Shankai, Guan Jian

机构信息

Department of Otorhinolaryngology, Sixth People's Hospital Affiliated to Shanghai Jiaotong University, Institute of Otorhinolaryngology, Shanghai Jiaotong University, Shanghai 200233, China.

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2011 Mar;25(5):226-31.

Abstract

OBJECTIVE

To explore the use of transnasal endoscopy and open surgical approaches for management of sinonasal and adjacent skull base benign fibro-osseous lesions, the surgical methods, precautions, clinical efficacies were also described.

METHOD

Fifteen patients were reviewed, including osteoma in 6 cases, Ossifying fibroma in 2 cases and fibrous dysplasia in 7 cases. Analyzed the pathological features and CT images, and to select surgical approach according to the location and extent of lesions. Eleven patients were operated through transnasal endoscopic procedure, including 7 cases with ipsilateral nasal approach and 4 cases with extended binasal approach; 4 cases with open surgical approach, including trans-eyebrow approach in 1 case and bicoronal approach in 3 cases.

RESULT

All patients were followed up for 2 months to 4 years, gross resection of lesions in 10 cases but partial resection in 5 cases with fibrous dysplasia. The clinical symptoms and facial deformity in all cases were eliminated or significantly relieved postoperatively. Cerebrospinal fluid leakage occurred in 1 case, was successfully repaired during the endoscopic operation. Preoperative diplopia in 3 cases, 2 cases disappeared after six months, one case was improved significantly. There were no postoperative orbital or intracranial complications.

CONCLUSION

Surgery is an effective means to resect lesions which had obviously clinical symptoms. The location and extent of lesions were the decisive factor to choose an open or endoscopic approach. Endoscopic sinus surgery can manage the midline skull base lesions which extend from the posterior wall of the frontal sinus to the clivus, well the open surgical approach is suitable for lesions locating the area beyond the medial orbital wall. No matter choosing which approach, osteoma, ossifying fibroma can be completely removed. For the fibrous dysplasia, as an extensive but self-limiting lesion, the surgery is performed only for relieving symptoms and facial deformity. So the partial resection is preferred and reasonable other than radical total resection. Even the severe fibrous dysplasia lesions caused the optic canal stenosis but present normal vision, it is unnecessary to perform prophylactic decompression of the optic nerve.

摘要

目的

探讨经鼻内镜及开放手术方法治疗鼻窦及相邻颅底良性纤维骨性病变的应用,描述手术方法、注意事项及临床疗效。

方法

回顾性分析15例患者,其中骨瘤6例,骨化性纤维瘤2例,骨纤维异常增殖症7例。分析其病理特征及CT图像,根据病变部位及范围选择手术方式。11例行经鼻内镜手术,其中同侧鼻腔入路7例,扩大双侧鼻腔入路4例;4例行开放手术,其中经眉弓入路1例,双冠状入路3例。

结果

所有患者随访2个月至4年,10例病变全切,5例骨纤维异常增殖症行部分切除。术后所有患者临床症状及面部畸形均消失或明显缓解。1例发生脑脊液漏,在内镜手术中成功修复。术前3例有复视,2例6个月后消失,1例明显改善。无术后眼眶或颅内并发症。

结论

手术是切除有明显临床症状病变的有效手段。病变的部位及范围是选择开放或内镜手术方式的决定性因素。内镜鼻窦手术可处理从额窦后壁至斜坡的中线颅底病变,开放手术则适用于位于眶内侧壁以外区域的病变。无论选择哪种手术方式,骨瘤、骨化性纤维瘤均可完全切除。对于骨纤维异常增殖症,因其病变广泛但具有自限性,手术仅为缓解症状及面部畸形,故首选部分切除而非根治性全切。即使严重的骨纤维异常增殖症病变导致视神经管狭窄但视力正常,也无需进行预防性视神经减压。

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