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[骨血管内皮瘤:关于一例解剖临床观察报告]

[Hemangioendothelioma of bone: A propos of an anatamo-clinical observation].

作者信息

Boccara M, Foucault D, de Maricourt D, Gerbal J L, Mazabraud A, Quillard J, Manigand G, Deparis M

出版信息

Sem Hop. 1978;54(41-42):1278-82.

PMID:216109
Abstract

Malignant hemangioendothelioma, localised to the skeleton of the lower limbs, to the exclusion of any other bony or visceral involvement, complicated by hemolytic anemia and spontaneous fractures, edl to death in spite of bilateral amputation, less than one year after its chance discovery. The multifocal character of the bony lesions, which is common, may suggest either rapidly developing metastases, or multicentric development of the tumour. The clinical, radiological and laboratory signs--pure osteolysis of large size without condensation nor periostosis, are not specific. Pathological examination permits recognition of the vascular origin of the tumour but does not always permit one to recognize its malignant nature. Treatment, which is mainly surgical, is often ineffective.

摘要

恶性血管内皮瘤,局限于下肢骨骼,无任何其他骨骼或内脏受累,并发溶血性贫血和自发性骨折,尽管进行了双侧截肢,但自偶然发现后不到一年便死亡。骨病变的多灶性很常见,这可能提示快速发展的转移瘤,或肿瘤的多中心发展。临床、放射学和实验室体征——大面积单纯骨质溶解,无骨质增生或骨膜反应,并不具有特异性。病理检查可识别肿瘤的血管起源,但并不总能识别其恶性性质。主要采用手术治疗,往往无效。

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