Garcia J, Avila-Sakar A J, Stefani E
Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX 77030.
Pflugers Arch. 1990 Apr;416(1-2):210-2. doi: 10.1007/BF00370245.
Voltage clamp experiments were conducted in frog skeletal muscle using repetitive stimulation protocols. The activation rate of Ca2+ currents increased by prepulses to depolarizing potentials or by stimulating the fiber with a frequency of 1.7 Hz at 0 mV. The effect was observable with Ca2+ or Ba2+ ions, and was clearly voltage-dependent. Physiologically, it is relevant that such activation rate increase can take place during a train of action potentials.
使用重复刺激方案在青蛙骨骼肌中进行电压钳实验。通过预脉冲至去极化电位或在0 mV处以1.7 Hz的频率刺激纤维，Ca2+电流的激活速率增加。Ca2+或Ba2+离子可观察到这种效应，并且明显依赖于电压。在生理上，这种激活速率增加可在一系列动作电位期间发生是相关的。
