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慢性血液透析患儿的血管通路:斯洛文尼亚的经验

Vascular access in children on chronic hemodialysis: a Slovenian experience.

作者信息

Rus Rina R, Novljan Gregor, Buturović-Ponikvar Jadranka, Kovač Janko, Premru Vladimir, Ponikvar Rafael

机构信息

Department of Pediatric Nephrology, University Medical Center, Ljubljana, Slovenia.

出版信息

Ther Apher Dial. 2011 Jun;15(3):292-7. doi: 10.1111/j.1744-9987.2011.00954.x.

Abstract

The aim of our study was to report our experience with arteriovenous fistulas (AVFs) and non-cuffed central venous catheters (CVCs) in children and adolescents with end-stage renal disease (ESRD) on hemodialysis (HD). The children with ESRD (18 years or younger) who were hemodialyzed at the Center of Dialysis and Transplantation, Children's Hospital, Ljubljana, in the period between December 1998 and December 2010 were included in our retrospective study. We recorded the data considering the CVCs and AVFs used for HD. Thirty-one children (13 females, 18 males) with ESRD received HD treatment. The mean patient age when HD was started was 13.3 ± 3.4 years. Altogether, 35 AVFs were created, and the primary failure rate was 25.7% (9/35). The time to maturation was 4.0 ± 2.5 months. The mean patency of the AVF was 42.5 ± 51.9 months. Seventy-seven CVCs (non-cuffed) were inserted in the observation period; 89.6% of the CVCs were inserted in the jugular vein, and citrate locking was used in the interdialysis period. The CVCs were removed after 0.1-17.4 months (3.6 ± 3.7 months). The incidence of bacteremia was 0.9 episodes per 1000 catheter days. The preferred vascular accesses for pediatric hemodialysis are native AVFs; however, a single lumen, non-cuffed, citrate-locked CVC placed in a jugular vein can be acceptable as a long-term vascular access when AVF cannot be constructed or used.

摘要

我们研究的目的是报告我们在终末期肾病(ESRD)接受血液透析(HD)的儿童和青少年中使用动静脉内瘘(AVF)和无套囊中心静脉导管(CVC)的经验。1998年12月至2010年12月期间在卢布尔雅那儿童医院透析与移植中心接受血液透析的ESRD儿童(18岁及以下)被纳入我们的回顾性研究。我们记录了用于HD的CVC和AVF的数据。31名ESRD儿童(13名女性,18名男性)接受了HD治疗。开始HD时的平均患者年龄为13.3±3.4岁。共创建了35个AVF,初级失败率为25.7%(9/35)。成熟时间为4.0±2.5个月。AVF的平均通畅时间为42.5±51.9个月。观察期内插入了77根CVC(无套囊);89.6%的CVC插入颈静脉,透析间期使用枸橼酸盐封管。CVC在0.1 - 17.4个月(3.6±3.7个月)后拔除。菌血症发生率为每1000导管日0.9次发作。小儿血液透析的首选血管通路是自体AVF;然而,当无法构建或使用AVF时,置于颈静脉的单腔、无套囊、枸橼酸盐封管的CVC可作为长期血管通路。

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