全基因组遗传图谱研究中的多种表型。
Multiple phenotypes in genome-wide genetic mapping studies.
机构信息
Key Laboratory of Mental Health Institute of Psychology, Chinese Academy of Sciences, Beijing 100101, China.
出版信息
Protein Cell. 2011 Jul;2(7):519-22. doi: 10.1007/s13238-011-1059-5. Epub 2011 Jun 6.
Abstract
For many psychiatric and other traits, diagnoses are based on a number of different criteria or phenotypes. Rather than carrying out genetic analyses on the final diagnosis, it has been suggested that relevant phenotypes should be analyzed directly. We provide an overview of statistical methods for the joint analysis of multiple phenotypes in case-control association studies.
摘要
对于许多精神疾病和其他特征，诊断是基于许多不同的标准或表型。与其对最终诊断进行基因分析，有人建议直接分析相关的表型。我们提供了在病例对照关联研究中联合分析多个表型的统计方法概述。
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