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伽玛刀治疗中的准直稳定性和解剖学质量保证

Frame stability and anatomical QA in radiosurgery.

机构信息

Division of Neurosurgery, National University Hospital, Singapore, Singapore.

出版信息

Acta Neurochir (Wien). 2011 Nov;153(11):2265-70. doi: 10.1007/s00701-011-1067-5. Epub 2011 Jun 18.

Abstract

OBJECTIVES

The aim of the study was to analyze whether the fixation of the stereotactic frame is stable and whether the location of the treated target coincides with its anatomical location during Gamma Knife(®) surgery (GKS).

MATERIALS AND METHODS

Stereotactic MR examinations using the same high-resolution MRI protocol were performed before and after GKS in 18 consecutive patients. The stereotactic (x,y,z) coordinates for three different anatomical landmarks were independently defined three times in each study for each landmark of the images taken before and after GKS by two of the authors, resulting in a total of 648 coordinate definitions.

RESULTS

The uncertainty in the readings of the coordinates for the anatomical landmarks was of the same magnitude as the difference in the coordinates before and after GKS in all but one patient. The differences in this one case were due to MR distortion and not to repositioning of the frame. The difference in the coordinates before and after treatment was not affected by the removal of one of the frontal fixation screws in one of the patients.

CONCLUSIONS

The stereotactic frame position is stable and does not move.

摘要

目的

本研究旨在分析伽玛刀(GKS)手术中立体定向框架的固定是否稳定,以及治疗靶区的位置是否与其解剖位置一致。

材料与方法

18 例连续患者在 GKS 前后均进行了相同高分辨率 MRI 方案的立体定向 MRI 检查。两位作者分别独立地对三个不同解剖标志的立体定向(x,y,z)坐标进行了 3 次定义,每个标志的图像在 GKS 前后各进行了一次定义,总共进行了 648 次坐标定义。

结果

除 1 例患者外,所有患者的解剖标志坐标读数的不确定性与 GKS 前后坐标的差异相同。在这一个病例中,差异是由于 MR 失真引起的,而不是框架的重新定位。在 1 例患者中去除一个额部固定螺钉后,治疗前后的坐标差异不受影响。

结论

立体定向框架位置稳定且不会移动。

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