Suppr超能文献

[创伤患者医院获得性肺炎的微生物谱]

[Microbial spectrum of nosocomial pneumonia in traumatological patients].

作者信息

Avazashvili N, Nozadze T, Chikviladze D, Gachechiladze Kh, Metreveli D, Mikeladze M

机构信息

Department of Traumatology and Orthopedics, Tbilisi State Medical University, Georgia.

出版信息

Georgian Med News. 2011 May(194):76-9.

Abstract

In this article there are given results of microbiological investigation of nosocomial pneumonia agents, microbial structure. Investigation was held in 727 cases of traumatological patients treated because of hip replacement or osteosinthesis of limbs. Complications with nosocomial pneumonia was found in 27 cases (3,7%). In 27 cases of diagnosed pneumonia, 66 microbial strains were isolated. In 4 cases (14,8%) was detected mono infection, different microbial association were isolated in 23 cases (85,2%) - 2 microbes in 7 and 3 microbes in 16 cases. Microbial structure was presented by: S.aureus (27,3%), Kl.pneumoniae (19.7%), S. pneumoniae (15,2%), A. baumanii (10,6%), E. coli (4,6%), enterobacter spp. (9,1%), P. aeruginosa (13,6%). Study of sensitiveness/resistance of separated stains to different groups of antibiotics showed, that micro organisms have high level of resistance to antibiotics and also pan-resistance. So, success of antimicrobial therapy depends on prompt and correct choice of antibiotics, based on aetiology of infection and sensitiveness to antibiotics. In cases of empirical administration, it is necessary to use antibiotics with high level of activity against pneumonia agents - carbapenems, and in case of high probability of MRSA - it is better to use linezolid or vancomicin.

摘要

本文给出了医院获得性肺炎病原体的微生物学调查结果及微生物结构。调查针对727例因髋关节置换或四肢骨固定术接受治疗的创伤患者进行。发现27例(3.7%)出现医院获得性肺炎并发症。在27例确诊肺炎病例中,分离出66株微生物菌株。4例(14.8%)检测到单一感染,23例(85.2%)分离出不同的微生物组合——7例为2种微生物,16例为3种微生物。微生物结构如下:金黄色葡萄球菌(27.3%)、肺炎克雷伯菌(19.7%)、肺炎链球菌(15.2%)、鲍曼不动杆菌(10.6%)、大肠杆菌(4.6%)、肠杆菌属(9.1%)、铜绿假单胞菌(13.6%)。对分离菌株对不同抗生素组的敏感性/耐药性研究表明,微生物对抗生素具有高度耐药性甚至泛耐药性。因此,抗菌治疗的成功取决于根据感染病因和对抗生素的敏感性及时、正确地选择抗生素。在经验性用药的情况下,有必要使用对肺炎病原体具有高活性的抗生素——碳青霉烯类,而在耐甲氧西林金黄色葡萄球菌(MRSA)可能性较高的情况下,最好使用利奈唑胺或万古霉素。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验