Department of Obstetrics and Gynecology, Mansoura University, Mansoura, Egypt.
Arch Gynecol Obstet. 2012 Feb;285(2):469-71. doi: 10.1007/s00404-011-1946-2. Epub 2011 Jun 24.
To study the outcome of fertility conserving surgery for ovarian tumors in children and young adults (≤ 20 years) over 6 years (2003-2009).
This prospective study included 183 patients diagnosed with ovarian cysts or tumors requiring surgical excision. Ovarian cystectomy/ovariectomy was carried out followed by frozen section histopathology. Malignant cases were subjected to staging laparotomy and fertility sparing surgery.
The median age at diagnosis was 17 years (range 7-20 years). 160/183 (87.4%) were non-neoplastic ovarian cysts or benign tumors. In 131/160 (81.8%) of non-neoplastic and benign tumors, it was possible to preserve the affected ovary. Twenty cases (11%) were diagnosed as primary malignant ovarian tumors, 2/183 (1.1%) were borderline tumors and 1 case (0.55%) was metastatic colonic carcinoma. The median follow up of cases with primary malignant ovarian tumors was 36 months. During this period, two recurrences (9.1%) were detected, both of the germ cell type (immature teratoma and yolk sac tumor). Recurrent cases were managed by local excision and lymph node sampling followed by chemotherapy.
Fertility sparing surgery for malignant ovarian tumors in children and young adults has excellent prognosis and should be attempted whenever possible.
研究 6 年期间（2003-2009 年）对≤20 岁的儿童和青年患者实施保留生育功能的卵巢肿瘤手术的结局。
本前瞻性研究纳入了 183 例诊断为卵巢囊肿或需手术切除的肿瘤的患者。进行卵巢囊肿切除术/卵巢切除术，然后进行冷冻切片组织病理学检查。恶性病例行分期腹腔镜检查和保留生育功能的手术。
诊断时的中位年龄为 17 岁（范围 7-20 岁）。160/183（87.4%）例为非肿瘤性卵巢囊肿或良性肿瘤。在 160 例非肿瘤性和良性肿瘤中，有 131/160（81.8%）例能够保留受影响的卵巢。20 例（11%）诊断为原发性恶性卵巢肿瘤，2/183（1.1%）例为交界性肿瘤，1 例（0.55%）例为转移性结直肠癌。原发性恶性卵巢肿瘤病例的中位随访时间为 36 个月。在此期间，发现 2 例（9.1%）复发，均为生殖细胞类型（未成熟畸胎瘤和卵黄囊瘤）。复发病例通过局部切除和淋巴结取样后进行化疗进行治疗。
对于儿童和青年的恶性卵巢肿瘤，保留生育功能的手术具有良好的预后，应尽可能尝试。
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