Erdem Arzu Pinar, Guven Yeliz, Balli Beyza, Ilhan Banu, Sepet Elif, Ulukapi Isin, Aktoren Oya
Department of Pedodontics, Istanbul University, Istanbul, Turkey.
Pediatr Dent. 2011 Mar-Apr;33(2):165-70.
The purpose of this study was to evaluate the total success rates of mineral trioxide aggregate (MTA), ferric sulfate (FS), and formocresol (FC) as pulpotomy agents in primary molars.
A randomized, split-mouth study design was used in 32 healthy 5- to 7-year-old children with 128 carious primary molars without clinical or radiographic evidence of pulp degeneration. The pulpotomy agents were assigned as follows: Group 1=MTA; Group 2=FS; Group 3=1:5 diluted Buckley's FC; and Group 4=zinc oxide eugenol (ZOE) base. Clinical and radiographic follow-up at 6, 12, and 24 months used the following criteria: pain; swelling; sinus tract; mobility; internal root resorption; and furcation and/or periapical bone destruction. The data were analyzed using chi-square.
No significant differences in success rates were found among the groups at 6 and 12 months. Success rates in groups 1 to 4 at 24 months were 96%, 88%, 88%, and 68% respectively. There was a significant difference (P<.001) between the MTA and ZOE groups at 24 months.
ZOE, as the only pulpotomy medicament, had a significantly lower success rate than MTA. No significant differences were observed, among the 3 experimental materials (MTA, FC, and FS) at 2 years follow-up.
本研究旨在评估三氧化矿物凝聚体（MTA）、硫酸铁（FS）和甲醛甲酚（FC）作为乳牙活髓切断术药物的总体成功率。
采用随机、双侧对照研究设计，对32名5至7岁健康儿童的128颗龋坏乳牙进行研究，这些乳牙无牙髓退变的临床或影像学证据。将活髓切断术药物分配如下：第1组 = MTA；第2组 = FS；第3组 = 1:5稀释的巴克利FC；第4组 = 氧化锌丁香酚（ZOE）糊剂。在6、12和24个月时进行临床和影像学随访，采用以下标准：疼痛；肿胀；窦道；松动度；牙根内吸收；以及根分叉和/或根尖周骨破坏。使用卡方检验分析数据。
在6个月和12个月时，各组成功率无显著差异。第1至4组在24个月时的成功率分别为96%、88%、88%和68%。在24个月时，MTA组和ZOE组之间存在显著差异（P <.001）。
ZOE作为唯一的活髓切断术药物，成功率显著低于MTA。在2年随访中，3种实验材料（MTA、FC和FS）之间未观察到显著差异。
