Department of Ophthalmology, Centre Hospitalier de l'Université de Montréal (CHUM), Hôpital Notre-Dame, Montréal, Que., Canada.
Can J Ophthalmol. 2011 Apr;46(2):164-8. doi: 10.3129/i10-103.
To describe the characteristics, indications, complications, and outcomes of the patients who underwent Boston type 1 keratoprosthesis (KPro) surgery at the Université de Montréal affiliated Notre-Dame Hospital.
Retrospective case series.
Forty-seven eyes of 43 patients who underwent KPro surgery.
The charts of all patients who underwent KPro surgery at Notre-Dame Hospital between October 2008 and February 2010 were retrospectively reviewed. Preoperative, intraoperative, and postoperative parameters were collected and analyzed.
The indication for Boston type 1 KPro was corneal graft failure in 27 eyes; 20 eyes had KPro as a primary procedure. Preoperative diagnoses included aniridia (34%), mechanical trauma (11%), infections (9%), surgery-related bullous keratopathy (9%), chemical burns (9%), corneal dystrophies (9%), and Stevens-Johnson syndrome (2%). A known history of glaucoma was present in 36 eyes (77%). Median preoperative best-corrected visual acuity (BCVA) was hand motion (range, 20/100 to light perception). The assembly of the KPro and surgery were uneventful in all cases. Mean follow-up was 10±5 months. MedianBCVA at last follow-up was 20/150 (range, 20/30 to no light perception). The device retention rate was 100% at the end of the follow-up period. Postoperative complications included retroprosthetic membrane in 12 eyes (26%) and glaucoma progression in 11 eyes (23%).
Our study demonstrates an excellent retention rate of the Boston type 1 KPro and an improvement of BCVA in the majority of patients. Many patients undergoing KPro surgery have ocular comorbidities that require ongoing care to prevent further vision loss following KPro surgery.
描述在蒙特利尔大学附属诺特丹圣母医院接受波士顿 1 型角膜假体(KPro)手术的患者的特征、适应证、并发症和结局。
回顾性病例系列。
43 例患者的 47 只眼接受了 KPro 手术。
回顾性分析 2008 年 10 月至 2010 年 2 月在诺特丹医院接受 KPro 手术的所有患者的病历。收集并分析术前、术中及术后的参数。
27 只眼因角膜移植失败而接受波士顿 1 型 KPro,20 只眼作为原发性手术。术前诊断包括无虹膜(34%)、机械性创伤(11%)、感染(9%)、与手术相关的大泡性角膜病变(9%)、化学烧伤(9%)、角膜营养不良(9%)和史蒂文斯-约翰逊综合征(2%)。36 只眼(77%)有已知青光眼病史。术前最佳矫正视力(BCVA)中位数为手动(范围 20/100 至光感)。所有病例的 KPro 装配和手术均顺利进行。平均随访时间为 10±5 个月。末次随访时的 BCVA 中位数为 20/150(范围 20/30 至无光感)。随访期末,器械保留率为 100%。术后并发症包括 12 只眼(26%)出现后发性人工膜和 11 只眼(23%)出现青光眼进展。
我们的研究表明,波士顿 1 型 KPro 的保留率很高,大多数患者的 BCVA 得到改善。许多接受 KPro 手术的患者存在眼部合并症,需要持续治疗,以防止 KPro 手术后视力进一步下降。