Soleimanpour Hassan, Hassanzadeh Kamaleddin, Mohammadi Dawood Agha, Vaezi Hassan, Esfanjani Robab Mehdizadeh
Emergency Medicine Department, Tabriz University of Medical Sciences, Daneshgah Street, Tabriz 51664, Iran.
J Med Case Rep. 2011 Jun 29;5:256. doi: 10.1186/1752-1947-5-256.
We report a case series of successful treatment of intractable renal colic using parenteral lidocaine.
Because of inconsistent responses to standard treatment with opioids and non-steroidal anti-inflammatory drugs in patients with renal colic pain, we decided to begin a trial of a single intravenous dose of lidocaine (approximately 1.5 mg/kg) slowly in eight patients with intractable renal colic who were referred to our emergency medicine department. The patients were six men and two women with a mean age at diagnosis of 34.62 years (age range, 28 to 42 years). The patients were of Iranian ethnic origin. The patients' degree of pain, based on Visual Analog Scale score upon entering our emergency medicine department, was recorded 10, 20, and 30 minutes after lidocaine injection. The patients' degree of pain decreased from a mean Visual Analog Scale score (±SD) of 8.87 ± 0.99 (95% confidence interval (95% CI) 8.04 to 9.70) to a mean Visual Analog Scale score (±SD) of 1 ± 2.82 (95% CI -1.36 to 3.36) before and 30 minutes after lidocaine treatment, respectively. Two of eight patients experienced transient mild dizziness, and three of eight patients experienced minimal slurring of speech. No patient experienced serious adverse events.
Parenteral lidocaine treatment can reduce pain dramatically or subtly.
我们报告了一系列使用胃肠外利多卡因成功治疗顽固性肾绞痛的病例。
由于肾绞痛患者对阿片类药物和非甾体抗炎药的标准治疗反应不一致,我们决定对转诊至我们急诊科的8例顽固性肾绞痛患者缓慢静脉注射单剂量利多卡因(约1.5mg/kg)进行试验。患者中有6名男性和2名女性,诊断时的平均年龄为34.62岁(年龄范围为28至42岁)。患者为伊朗裔。根据进入急诊科时的视觉模拟量表评分记录患者在利多卡因注射后10、20和30分钟时的疼痛程度。利多卡因治疗前和治疗30分钟后,患者的疼痛程度分别从平均视觉模拟量表评分(±标准差)8.87±0.99(95%置信区间(95%CI)8.04至9.70)降至平均视觉模拟量表评分(±标准差)1±2.82(95%CI -1.36至3.36)。8例患者中有2例出现短暂轻度头晕,8例患者中有3例出现轻微言语含糊。无患者发生严重不良事件。
胃肠外利多卡因治疗可显著或轻微减轻疼痛。