Kawamura S, Kumasaka K, Sakuma Y, Ohhinata M, Kubo T, Sasou S
Department of Urology, Iwate Medical University.
Nihon Hinyokika Gakkai Zasshi. 1990 Sep;81(9):1412-5. doi: 10.5980/jpnjurol1989.81.1412.
The patient was a 61-year-old male who had undergone right nephrectomy for nephrolithiasis 35 years before. He had been on hemodialysis for 6 years for chronic renal failure caused by left renal staghorn calculus and hydronephrosis. He was admitted to our hospital because of macroscopic hematuria and sense of residual urine which had persisted for 3 months. Cystoscopic examination showed an extensive papillary tumor in the urinary bladder, which histologically was an adenocarcinoma. Giant left hydronephrosis associated with staghorn calculus noted by KUB and CT scan. Total cystectomy, intraoperative radiotherapy, and left nephrostomy were performed under the diagnosis of adenocarcinoma of the urinary bladder and left hydronephrosis. The bladder tumor was found to be a mucinous adenocarcinoma. The patient died from a cerebral hemorrhage on the 17th postoperative day. At autopsy, tumors were found in the pelvis of the left kidney and the middle and lower regions of the ureter, which were adenocarcinoma like the bladder tumor. Adenocarcinoma occurring simultaneously in the renal pelvis and bladder has not been previously reported to our knowledge, in Japan or elsewhere.
患者为61岁男性,35年前因肾结石接受了右肾切除术。他因左肾鹿角形结石和肾积水导致的慢性肾衰竭已接受血液透析6年。因肉眼血尿和残余尿感持续3个月而入住我院。膀胱镜检查显示膀胱内有广泛的乳头状肿瘤,组织学检查为腺癌。腹部平片(KUB)和CT扫描显示左肾巨大积水并伴有鹿角形结石。在诊断为膀胱腺癌和左肾积水后,进行了全膀胱切除术、术中放疗和左肾造瘘术。发现膀胱肿瘤为黏液腺癌。患者术后第17天死于脑出血。尸检时,在左肾盂和输尿管中下段发现肿瘤,均为腺癌,与膀胱肿瘤相似。据我们所知,日本及其他地方此前均未报道过肾盂和膀胱同时发生腺癌的情况。