[从脑膜炎患者脑脊液中分离出的流感嗜血杆菌菌株的生化特性及抗生素耐药表型]

[The biochemical characteristics and antibiotic resistance phenotypes of strains of H. influenza isolated from the CSF of patients with meningitis].

作者信息

Mihancea N, Popa A C

机构信息

Institutul Cantacuzino, Bucureşti.

出版信息

Rev Ig Bacteriol Virusol Parazitol Epidemiol Pneumoftiziol Bacteriol Virusol Parazitol Epidemiol. 1990 Jan-Mar;35(1):65-70.

PMID:2173122

Abstract

The paper reports on the biochemical characteristics and the antibiotic resistant phenotypes in 18 strains of H. influenza (17 b serotype and a strain of c serotype) isolated from the CSF of the patients with purulent meningitis. The following were found: --all the 16 viable strains have homogeneous biochemical characteristics, typical for H. influenza; --the viable strains were: 7 biotype, 4 biotype II, 1 biotype III, 3 biotype IV and 1 biotype VII; --68.8% of the strains had the following antibiotic resistant phenotypes: Ap, Km, Rf, ApKm, ApRf, ApKmTc, ApKmRfT and ApCmFrKmRfTc; --the strains of the biotypes II and IV have the highest resistance to antibiotics, as concerns frequency and phenotype; --the frequency of the resistant strains is of 56.2% for ampicilline, 18.7% for tetracycline, 31.2% for rifampicine and 6.2% for cholarmphenicol.

摘要

该论文报道了从化脓性脑膜炎患者脑脊液中分离出的18株流感嗜血杆菌（17株b血清型和1株c血清型）的生化特性及抗生素耐药表型。结果如下：——16株存活菌株具有流感嗜血杆菌典型的均一生化特性；——存活菌株包括：7株生物型I、4株生物型II、1株生物型III、3株生物型IV和1株生物型VII；——68.8%的菌株具有以下抗生素耐药表型：氨苄青霉素（Ap）、卡那霉素（Km）、利福平（Rf）、ApKm、ApRf、ApKmTc、ApKmRfT和ApCmFrKmRfTc；——就频率和表型而言，生物型II和IV的菌株对抗生素的耐药性最高；——耐药菌株对氨苄青霉素的频率为56.2%，对四环素为18.7%，对利福平为31.2%，对氯霉素为6.2%。