Martínez León M I
Sección de Radiología Pediátrica, Servicio de Radiodiagnóstico, Hospital Materno-Infantil, Complejo Hospitalario Universitario Carlos Haya, Málaga, España.
Radiologia. 2013 Nov-Dec;55(6):541-5. doi: 10.1016/j.rx.2010.12.018. Epub 2011 Jul 5.
Radiotherapy forms part of most therapeutic, preventive, and conditioning regimens in pediatric oncology. Numerous late secondary effects of cranial radiation are well known. However, radiation-induced cavernous angiomas (RICA) have been reported only sporadically and even fewer cases of earlier presentation of RICA have been reported. In this brief report, we describe a RICA that appeared in a boy treated for a CNS tumor (an infratentorial anaplastic ependymoma) after a short latency period between the end of radiotherapy and the development of the RICA. We comment on the different variables proposed to explain the formation of these lesions, as well as on their imaging features, treatment, prognosis, and follow-up.
放射治疗是儿科肿瘤学中大多数治疗、预防和预处理方案的一部分。颅脑放疗的许多晚期继发效应是众所周知的。然而,辐射诱发的海绵状血管瘤(RICA)仅偶尔有报道,更早出现RICA的病例报道则更少。在本简要报告中,我们描述了1例RICA,该病例出现在1名接受中枢神经系统肿瘤(幕下间变性室管膜瘤)治疗的男孩中,放疗结束至RICA出现的潜伏期较短。我们对为解释这些病变形成而提出的不同变量,以及它们的影像学特征、治疗、预后和随访情况进行了评论。