Jahn K, Gerstner A O H, Hartmann W, Schade G
Abteilung für Phoniatrie und Pädaudiologie, Universitäts-HNO-Klinik Bonn, Sigmund-Freud-Str. 25, 53105, Bonn, Deutschland.
HNO. 2012 Apr;60(4):352-4. doi: 10.1007/s00106-011-2340-x.
Chronic lymphocytic leukemia (CLL) is the most common form of leukemia in the Western World. It belongs to the low-grade non-Hodgkin lymphomas and is characterized by clonal reproduction of mature small-cell non-functional B-lymphocytes. CLL affects men somewhat more often than women and the average age at onset is over 50 years. In addition to regional lymph node swelling, typical symptoms include hepatosplenomegaly, leukocytosis and skin disorders such as eczema and pruritus. Manifestations in the oropharynx or hypopharynx are rare but should be kept in mind in the differential diagnosis.
慢性淋巴细胞白血病(CLL)是西方世界最常见的白血病形式。它属于低度非霍奇金淋巴瘤,其特征是成熟的无功能小细胞B淋巴细胞的克隆性增殖。CLL在男性中的发病率略高于女性,平均发病年龄超过50岁。除局部淋巴结肿大外,典型症状还包括肝脾肿大、白细胞增多以及皮肤疾病,如湿疹和瘙痒。口咽或下咽的表现很少见,但在鉴别诊断时应予以考虑。