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[慢性阻塞性肺疾病急性加重患者使用头盔式与面罩式无创机械通气的比较]

[Comparison of non-invasive mechanical ventilation with helmet or face mask in patients with acute exacerbation of chronic obstructive pulmonary disease].

作者信息

Ali Achmet, Türkmen Aygen, Turgut Namigar, Altan Aysel, Sari Tarik

机构信息

Department of Anaesthesiology and Reanimation, Okmeydani Training and Research Hospital, Istanbul, Turkey.

出版信息

Tuberk Toraks. 2011;59(2):146-52. doi: 10.5578/tt.738.

Abstract

Exacerbation of chronic obstructive pulmonary disease (COPD) is one of the frequent causes of acute respiratory failure. In our study, we aimed to compare helmet with face mask in noninvasive mechanical ventilation (NIMV) on patients who had acute respiratory failure because of exacerbation of COPD in intensive care unit (ICU). Thirty patients, taken into ICU for exacerbation of COPD, were included in the study. Patients were divided into two groups as face mask group (Group Y) and helmet group (Group H). Appropriate mechanical ventilation settings were recorded after the starting period and NIMV was applied to patients continuously for two hours with these settings. Respiratory frequency (f), blood gas (PaO(2), PaCO(2), PH) and PaO(2)/FiO(2) values and hemodynamic data of all patients were recorded periodically. Compliance of patients were evaluated with patient tolerance scale (PTS). Duration of stay of the patients in ICU and complications were also noted. Demographic characteristics of patients, mechanical ventilator settings and hemodynamic data of the patients in the two groups were found to be similar (p>0.05). Frequency values measured during NIMV are also similar at all measurement times (p>0.05). It was determined that there was a remarkable decrease in respiratory frequency, in both groups after the application of NIMV (p< 0.001). There was no difference with respect to PaO(2), PH and PaO(2)/FiO(2) values at all measurement times, between groups (p> 0.05). PaCO(2) values in the beginning were similar in both groups but PaCO(2) measured at other measurement times for group H were statistically higher compared to the other group (p< 0.05). PTC score measured at during NIMV in group H were remarkably higher (p< 0.05). Helmet developed as an alternative to face mask has a better patient tolerance and accordingly in increases success rate in NIMV. But it must be keeping mind that the decrease in PaCO(2) value is slow with helmet.

摘要

慢性阻塞性肺疾病(COPD)急性加重是急性呼吸衰竭的常见原因之一。在我们的研究中,我们旨在比较头盔与面罩在重症监护病房(ICU)中对因COPD急性加重导致急性呼吸衰竭的患者进行无创机械通气(NIMV)时的效果。30例因COPD急性加重入住ICU的患者被纳入研究。患者被分为两组,即面罩组(Y组)和头盔组(H组)。在起始期后记录适当的机械通气设置,并使用这些设置对患者持续进行两小时的NIMV。定期记录所有患者的呼吸频率(f)、血气(PaO₂、PaCO₂、PH)和PaO₂/FiO₂值以及血流动力学数据。使用患者耐受量表(PTS)评估患者的耐受性。记录患者在ICU的住院时间和并发症。发现两组患者的人口统计学特征、机械通气设置和血流动力学数据相似(p>0.05)。在所有测量时间点,NIMV期间测量的频率值也相似(p>0.05)。确定在应用NIMV后,两组患者的呼吸频率均显著降低(p<0.001)。在所有测量时间点,两组之间的PaO₂、PH和PaO₂/FiO₂值没有差异(p>0.05)。两组开始时的PaCO₂值相似,但H组在其他测量时间点测量的PaCO₂与另一组相比在统计学上更高(p<0.05)。H组在NIMV期间测量的PTC评分显著更高(p<0.05)。作为面罩替代品开发的头盔具有更好的患者耐受性,因此提高了NIMV的成功率。但必须记住,使用头盔时PaCO₂值下降缓慢。

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