Debasish Basu, MD., DNB., Asst. Professor, Department of Psychiatry, Postgraduate Institute of Medical Education and Research, Chandigarh 160012.
Indian J Psychiatry. 1995 Jan;37(1):17-22.
The aim of the study was to assess two psychological parameters, sensation-seeking (SS) and alienation (AL), in a sample of thirty DSM-III diagnosed opiate dependence cases, and to compare them on these two parameters with two non-drug-abusing control groups, one from the patients own peer groups and the other from the general population. The opiate dependent subjects were found to score higher both on SS and AL than those in the control groups. Further, there was a gradient of the degree of correlation between these two psychological variables amongst the three groups studied. The opiate dependent group showed the highest positive correlation. The general population control group showed the lowest degree of correlation, and the self-matched control group was intermediate.These findings are consonant with an "SS-AL combination" hypothesis for the genesis of opiate addiction. Briefly, the hypothesis states that a higher sensation-seeking need, coupled with an inability to meet this need through socially sanctioned channels, leads on to repeated experiences with drug taking behavior, thus fostering dependence. The present study provides preliminary data supporting this hypothesis.
本研究的目的是评估三十名 DSM-III 诊断的阿片类药物依赖病例样本中的两个心理参数，即寻求刺激（SS）和异化（AL），并将它们与两个非药物滥用对照组进行比较，一个来自患者自身的同龄人群体，另一个来自普通人群。研究发现，阿片类药物依赖者在 SS 和 AL 两个参数上的得分均高于对照组。此外，在研究的三个组中，这两个心理变量之间的相关性程度呈梯度分布。阿片类药物依赖组显示出最高的正相关。普通人群对照组显示出最低的相关性程度，而自我匹配的对照组则处于中间水平。这些发现与阿片类药物成瘾的“SS-AL 组合”假说一致。简而言之，该假说指出，较高的寻求刺激需求，加上无法通过社会认可的渠道满足这种需求，会导致反复出现药物使用行为，从而促成依赖。本研究提供了支持该假说的初步数据。
