Kido Nobuhide, Kamegaya Chihiro, Omiya Tomoko, Wada Yuko, Takahashi Maya, Yamamoto Yasuhiko
Kanazawa Zoological Gardens, Kanazawa-ku, Yokohama-shi, Japan.
Parasitol Int. 2011 Dec;60(4):425-8. doi: 10.1016/j.parint.2011.06.023. Epub 2011 Jul 3.
Frequent outbreaks of Sarcoptes scabiei infestation in raccoon dogs (Nyctereutes procyonoides) have been reported in Japan. Although many raccoon dogs are brought to Kanazawa Zoological Garden (Yokohama, Kanagawa, Japan) because of S. scabiei infestation and debilitation, some of them die of asthenia. The clinical status of severely debilitated raccoon dogs must be determined to save their lives. In this study, we compared hematological and serum biochemical values between severely debilitated and nondebilitated raccoon dogs infested with S. scabiei. The total protein, albumin, glucose, and calcium values of debilitated raccoon dogs were significantly lower than those of nondebilitated raccoon dogs. On the other hand, debilitated raccoon dogs had significantly higher aspartate aminotransferase, total bilirubin, blood urea nitrogen, sodium, chloride, and phosphorus values than did nondebilitated raccoon dogs. The increase in the blood urea nitrogen value was particularly dramatic. The present study revealed that debilitated raccoon dogs infested with S. scabiei exhibited abnormal hematological values compared with nondebilitated raccoon dogs infested with S. scabiei. Clinically, the raccoon dogs developed malnutrition and sepsis if the mange infestation was untreated. Moreover, dehydration associated with appetite loss may have resulted in insufficient renal perfusion. These findings suggest that chronic S. scabiei infestations debilitated the raccoon dogs and resulted in physiological changes that were detected with hematological and serum biochemical tests.
在日本，已报道貉（Nyctereutes procyonoides）频繁爆发疥螨感染。尽管许多貉因疥螨感染和身体虚弱被带到金泽动物园（日本神奈川县横滨市），但其中一些死于虚弱。必须确定严重虚弱的貉的临床状况以挽救它们的生命。在本研究中，我们比较了严重虚弱和未虚弱的感染疥螨的貉的血液学和血清生化值。虚弱貉的总蛋白、白蛋白、葡萄糖和钙值显著低于未虚弱的貉。另一方面，虚弱貉的天冬氨酸转氨酶、总胆红素、血尿素氮、钠、氯和磷值显著高于未虚弱的貉。血尿素氮值的升高尤为显著。本研究表明，与未虚弱的感染疥螨的貉相比，严重虚弱的感染疥螨的貉表现出异常的血液学值。临床上，如果疥螨感染未得到治疗，貉会出现营养不良和败血症。此外，与食欲减退相关的脱水可能导致肾灌注不足。这些发现表明，慢性疥螨感染使貉身体虚弱，并导致血液学和血清生化检测可检测到的生理变化。
