Department of Biology, University of Eastern Finland, Joensuu Campus, P.O. Box 111, FI-80101 Joensuu, Finland.
Exp Parasitol. 2011 Sep;129(1):72-4. doi: 10.1016/j.exppara.2011.06.013. Epub 2011 Jul 3.
The present study had a practical goal. I aimed to determine whether praziquantel could reduce the production of Echinoparyphium aconiatum (Trematoda: Echinostomatidae) cercariae in infected snails Lymnaea stagnalis (Gastropoda: Lymnaeidae) without killing the hosts. Praziquantel is a broad-spectrum antihelminth agent. It caused a total cessation of cercaria shedding when the praziquantel concentration in the treatment bath was 10 mg/L and the treatment time was 30 h or longer. A next research step which has to be taken before giving detailed recommendations about using praziquantel for ceasing production of E. aconiatum cercariae in parasitized snails is to follow the survivorship and performance of treated snails after a praziquantel exposure for longer than in this medium-term (3 days) experiment.
本研究具有实际目的。我旨在确定吡喹酮是否可以在不杀死宿主的情况下减少感染的蜗牛（Lymnaea stagnalis）（Gastropoda：Lymnaeidae）中 Echinoparyphium aconiatum（Trematoda：Echinostomatidae）尾蚴的产生。吡喹酮是一种广谱抗蠕虫药。当处理浴中的吡喹酮浓度为 10mg/L 且处理时间为 30 小时或更长时间时，它会导致尾蚴完全停止脱落。在给出有关使用吡喹酮停止寄生蜗牛中 E. aconiatum 尾蚴产生的详细建议之前，必须采取下一步研究措施，即在该中期（3 天）实验之外，跟踪经吡喹酮处理的蜗牛的存活和表现。
