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基于多尺度有限元模型的心室辅助装置(POLVAD和POLVAD_EXT)的对比分析。

Comparative analysis of ventricular assist devices (POLVAD and POLVAD_EXT) based on multiscale FEM model.

作者信息

Milenin Andrzej, Kopernik Magdalena

机构信息

Department of Applied Computer Science and Modelling, AGH University of Science and Technology, Kraków, Poland.

出版信息

Acta Bioeng Biomech. 2011;13(2):13-23.

Abstract

The prosthesis - pulsatory ventricular assist device (VAD) - is made of polyurethane (PU) and biocompatible TiN deposited by pulsed laser deposition (PLD) method. The paper discusses the numerical modelling and computer-aided design of such an artificial organ. Two types of VADs: POLVAD and POLVAD_EXT are investigated. The main tasks and assumptions of the computer program developed are presented. The multiscale model of VAD based on finite element method (FEM) is introduced and the analysis of the stress-strain state in macroscale for the blood chamber in both versions of VAD is shown, as well as the verification of the results calculated by applying ABAQUS, a commercial FEM code. The FEM code developed is based on a new approach to the simulation of multilayer materials obtained by using PLD method. The model in microscale includes two components, i.e., model of initial stresses (residual stress) caused by the deposition process and simulation of active loadings observed in the blood chamber of POLVAD and POLVAD_EXT. The computed distributions of stresses and strains in macro- and microscales are helpful in defining precisely the regions of blood chamber, which can be defined as the failure-source areas.

摘要

该假体——搏动性心室辅助装置(VAD)——由聚氨酯(PU)以及通过脉冲激光沉积(PLD)方法沉积的生物相容性氮化钛(TiN)制成。本文讨论了这种人工器官的数值建模和计算机辅助设计。研究了两种类型的VAD:POLVAD和POLVAD_EXT。介绍了所开发计算机程序的主要任务和假设。引入了基于有限元方法(FEM)的VAD多尺度模型,并展示了两种版本VAD中血腔宏观尺度下的应力应变状态分析,以及应用商业有限元代码ABAQUS计算结果的验证。所开发的有限元代码基于一种模拟通过PLD方法获得的多层材料的新方法。微观尺度模型包括两个部分,即由沉积过程引起的初始应力(残余应力)模型以及对POLVAD和POLVAD_EXT血腔中观察到的主动载荷的模拟。宏观和微观尺度下计算得到的应力和应变分布有助于精确界定血腔区域,这些区域可被定义为故障源区域。

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