马蹄声和斑马：以“首发”精神病为表现的神经退行性疾病。
Hoofbeats and zebras: neurodegenerative disorder presenting as a "first episode" of psychosis.
机构信息
Department of Psychiatry, Yale University, School of Medicine, New Haven, CT 06519, USA.
出版信息
Gen Hosp Psychiatry. 2011 Jul-Aug;33(4):412.e1-3. doi: 10.1016/j.genhosppsych.2011.03.011. Epub 2011 May 5.
Abstract
Neurodegenerative disorders can include diverse neuropsychiatric symptoms. Here we present a case referred to a "first-episode" psychosis clinic with socio-occupational decline, auditory hallucinations and paranoid ideation who subsequently exhibited a rapid, severe cognitive and behavioral decline. The brain magnetic resonance imaging findings of the patient have shown a progressive cortical atrophy prominent in the frontal lobes due to a neurodegenerative disorder.
摘要
神经退行性疾病可包括多种神经精神症状。在此，我们报告了一例以社会职业功能下降、幻听和妄想为首发表现的“首发精神病”患者，随后出现了快速、严重的认知和行为能力下降。该患者的脑部磁共振成像检查结果显示，由于神经退行性疾病导致进行性皮质萎缩，以额叶明显。
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