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小儿活体肝移植中肝静脉重建的最佳技术是什么?单中心经验。

Which is the best technique for hepatic venous reconstruction in pediatric living-donor liver transplantation? Experience from a single center.

机构信息

Pediatric Surgery Division and Liver Transplantation Unit, Children's Institute, Hospital das Clinicas, University of Sao Paulo, Sao Paulo, Brazil.

出版信息

J Pediatr Surg. 2011 Jul;46(7):1379-84. doi: 10.1016/j.jpedsurg.2010.11.047.

Abstract

BACKGROUND/PURPOSE: The introduction of the piggyback technique for reconstruction of the liver outflow in reduced-size liver transplants for pediatric patients has increased the incidence of hepatic venous outflow block (HVOB). Here, we proposed a new technique for hepatic venous reconstruction in pediatric living-donor liver transplantation.

METHODS

Three techniques were used: direct anastomosis of the orifice of the donor hepatic veins and the orifice of the recipient hepatic veins (group 1); triangular anastomosis after creating a wide triangular orifice in the recipient inferior vena cava at the confluence of all the hepatic veins (group 2); and a new technique, which is a wide longitudinal anastomosis performed at the anterior wall of the inferior vena cava (group 3).

RESULTS

In groups 1 and 2, the incidences of HVOB were 27.7% and 5.7%, respectively. In group 3, no patient presented HVOB (P = .001). No difference was noted between groups 2 and 3.

CONCLUSIONS

Hepatic venous reconstruction in pediatric living-donor liver transplantation must be preferentially performed by using a wide longitudinal incision at the anterior wall of the recipient inferior vena cava. As an alternative technique, triangulation of the recipient inferior vena cava, including the orifices of the 3 hepatic veins, may be used.

摘要

背景/目的:在小儿减体积肝移植中,为重建肝流出道而引入的背驮式技术增加了肝静脉流出道阻塞(HVOB)的发生率。在此,我们提出了一种小儿活体肝移植中肝静脉重建的新技术。

方法

采用了三种技术:供肝静脉口与受体肝静脉口直接吻合(第 1 组);在所有肝静脉汇合处受体下腔静脉创建宽三角形口后行三角形吻合(第 2 组);以及一种新的技术,即在下腔静脉前壁行宽的纵向吻合(第 3 组)。

结果

第 1 组和第 2 组 HVOB 的发生率分别为 27.7%和 5.7%。第 3 组无 HVOB 发生(P =.001)。第 2 组和第 3 组之间无差异。

结论

小儿活体肝移植中肝静脉重建应优先采用受体下腔静脉前壁的宽纵向切口。作为替代技术,可采用包括 3 个肝静脉口在内的受体下腔静脉的三角切开术。

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