经直肠活检的Gleason评分与根治性前列腺切除术手术标本的Gleason评分之间的一致性
[Concordance between Gleason scores of trans rectal biopsies and the surgical piece of radical prostatectomy].
作者信息
Tapia Oscar, Bellolio Enrique, Roa Juan Carlos, Guzmán Pablo, Villaseca Miguel, Araya Juan Carlos
机构信息
Departamento de Anatomía Patológica, Facultad de Medicina, Universidad de La Frontera, Temuco, Chile.
出版信息
Rev Med Chil. 2011 Feb;139(2):171-6. Epub 2011 Jul 11.
BACKGROUND
Gleason pathological score in prostate cancer is an important prognostic indicator. However, the concordance between the score of trans rectal needle biopsies and the final score of the surgical piece may be variable.
AIM
To analyze the concordance between Gleason scores of trans rectal prostate biopsies and those of the surgical piece obtained after prostatectomy.
MATERIAL AND METHODS
Retrospective analysis of 168 pathological records of radical prostatectomies, performed between 1993 and 2009. All these patients had also a trans rectal biopsy performed previously. Patients with less than 12 tissue cylinders obtained during the trans rectal biopsy or incomplete data were not included in this analysis.
RESULTS
Sixty eight percent of trans rectal biopsies had Gleason scores that were concordant with those of the surgical piece. The score was higher or lower in 27 and 10% of biopsies, respectively.
CONCLUSIONS
Gleason scores of trans rectal biopsies and those of the surgical piece were concordant in 68% of cases in this series of pathological records.
背景
前列腺癌的Gleason病理评分是一项重要的预后指标。然而，经直肠穿刺活检的评分与手术标本的最终评分之间的一致性可能存在差异。
目的
分析经直肠前列腺活检的Gleason评分与前列腺切除术后手术标本的Gleason评分之间的一致性。
材料与方法
回顾性分析1993年至2009年间进行的168例根治性前列腺切除术的病理记录。所有这些患者此前均已进行过经直肠活检。经直肠活检获取组织圆柱少于12个或数据不完整的患者未纳入本分析。
结果
68%的经直肠活检的Gleason评分与手术标本的评分一致。活检评分分别在27%和10%的病例中高于或低于手术标本评分。
结论
在这一系列病理记录中，68%的病例经直肠活检的Gleason评分与手术标本的评分一致。
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