Balcı Yasemin Işık, Türk Meral, Ozgür Arzu, Küçüktaşçı Kazım
Pamukkale Üniversitesi Tıp Fakültesi, Pediatrik Hematoloji Bilim Dalı, Denizli, Türkiye, Turkey.
Turkiye Parazitol Derg. 2011;35(2):114-6. doi: 10.5152/tpd.2011.28.
Visceral Leishmaniasis (VL) in infancy is mostly seen between the ages of 2-4,and visceral infection causes long standing fever, weakness, weight loss, hepatosplenomegaly and pancytopenia. Leishmania infantum is responsible for VL in Turkey. In this study, 4 pediatric cases of VL were analysed retrospectively. Bone marrow aspirate was obtained in two cases and Leishmania amastigotes were not obtained in these cases. Leishmania antibodies by the indirect immun fluorescent antibody test (IFAT) were positive in all cases. We consider that IFAT was a suitable alternative to parasite detection in the conclusive diagnosis of visceral leishmaniasis in pediatric patients when strong clinical suspicion is present.
婴儿内脏利什曼病(VL)多见于2至4岁之间,内脏感染会导致长期发热、虚弱、体重减轻、肝脾肿大和全血细胞减少。婴儿利什曼原虫是土耳其VL的病原体。本研究回顾性分析了4例儿童VL病例。2例获取了骨髓穿刺液,但未发现利什曼无鞭毛体。所有病例通过间接免疫荧光抗体试验(IFAT)检测的利什曼抗体均为阳性。我们认为,当临床高度怀疑时,IFAT是儿科患者内脏利什曼病确诊诊断中寄生虫检测的合适替代方法。