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USP22 regulates cell proliferation by deubiquitinating the transcriptional regulator FBP1.
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A high-confidence interaction map identifies SIRT1 as a mediator of acetylation of USP22 and the SAGA coactivator complex.
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Far upstream element binding protein 1: a commander of transcription, translation and beyond.
Oncogene. 2013 Jun 13;32(24):2907-16. doi: 10.1038/onc.2012.350. Epub 2012 Aug 27.
9
Control of CCND1 ubiquitylation by the catalytic SAGA subunit USP22 is essential for cell cycle progression through G1 in cancer cells.
Proc Natl Acad Sci U S A. 2018 Oct 2;115(40):E9298-E9307. doi: 10.1073/pnas.1807704115. Epub 2018 Sep 17.
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Ubiquitin-specific peptidase 42 (USP42) functions to deubiquitylate histones and regulate transcriptional activity.
J Biol Chem. 2014 Dec 12;289(50):34862-70. doi: 10.1074/jbc.M114.589267. Epub 2014 Oct 21.

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Bioinformatic analysis of the role of USP22 expression in hepatocellular carcinoma.
Int J Clin Exp Pathol. 2025 Jul 15;18(7):287-301. doi: 10.62347/FXIN5300. eCollection 2025.
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Deubiquitinases as novel therapeutic targets for diseases.
MedComm (2020). 2024 Dec 13;5(12):e70036. doi: 10.1002/mco2.70036. eCollection 2024 Dec.
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USP22 regulates APL differentiation via PML-RARα stabilization and IFN repression.
Cell Death Discov. 2024 Mar 11;10(1):128. doi: 10.1038/s41420-024-01894-8.
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Deubiquitinases in cancer.
Nat Rev Cancer. 2023 Dec;23(12):842-862. doi: 10.1038/s41568-023-00633-y. Epub 2023 Nov 7.
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Deubiquitylating Enzymes in Cancer and Immunity.
Adv Sci (Weinh). 2023 Dec;10(36):e2303807. doi: 10.1002/advs.202303807. Epub 2023 Oct 27.

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Molecular basis of FIR-mediated c-myc transcriptional control.
Nat Struct Mol Biol. 2010 Sep;17(9):1058-64. doi: 10.1038/nsmb.1883. Epub 2010 Aug 15.
3
Gcn5 and SAGA regulate shelterin protein turnover and telomere maintenance.
Mol Cell. 2009 Aug 14;35(3):352-64. doi: 10.1016/j.molcel.2009.06.015.
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Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies.
Cell. 2008 Aug 22;134(4):668-78. doi: 10.1016/j.cell.2008.07.039.
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How the c-myc promoter works and why it sometimes does not.
J Natl Cancer Inst Monogr. 2008(39):41-3. doi: 10.1093/jncimonographs/lgn004.
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HDAC4 promotes growth of colon cancer cells via repression of p21.
Mol Biol Cell. 2008 Oct;19(10):4062-75. doi: 10.1091/mbc.e08-02-0139. Epub 2008 Jul 16.

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