Rubin Michel Risnic, Dantas Paulo Elias C, Nishiwaki-Dantas M Cristina, Felberg Sergio
Departamento de Oftalmologia, Irmandade da Santa Casa de Misericórdia de São Paulo, SP, Brasil.
Arq Bras Oftalmol. 2011 Mar-Apr;74(2):123-6. doi: 10.1590/s0004-27492011000200011.
To compare the efficacy of conjunctival autograft surgery with the attachment to the scleral bed using fibrin tissue adhesive or mononylon 10-0 suture after resection of primary pterygium.
A comparative, prospective and randomized clinical trial was performed in 47 eyes of 47 patients with primary medial located pterygium. Group 1 (adhesive) was composed by 21 patients that underwent conjunctival autograft closure with fibrin tissue adhesive (Quixil™) and Group 2 (suture) was composed by 26 patients that underwent pterygium surgery with mononylon 10-0 (Ethicon(®)) suture (suture group) after pterygium excision. All surgeries were performed by the same surgeon. Patients were assessed on the preoperative period and on the 1(st), 14(th) and 21(st) postoperative days. They were followed-up with a questionnaire of ocular discomfort and by the surgical time spent, ocular hyperemia, complications and recurrence signals, being the recurrence also evaluated at the 6th postoperative month. Data were submitted to statistical analysis. A value of p<0.005 was considered statistically significant.
The average surgical time was 19.05 ± 6.12 minutes in group 1 (glue) and 48.15 ± 7.13 minutes in the group 2 (suture) (p<0.001). The ocular discomfort scale analysis showed a lower score in the 1(st) (p<0.005), 7(th) (p<0.001) and 21(th) (p<0.001) postoperative days in group 1. Ocular hyperemia was less intense in all periods of this study in group 1 (p<0.001). Complications were one in each group and both were managed with clinical treatment until the 21(th) postoperative day. There was one recurrence in group 1 and two in group 2 until the 6(th) postoperative month.
In the surgical management of primary pterygium, fibrin tissue adhesive attached the conjunctival autograft, decreased the surgical time and diminished the conjunctival hyperemia and ocular discomfort with similar recurrences on the postoperative period, compared to fixation with mononylon 10.0 suture, proving to be an excellent option for conjunctival autograft attachment in primary pterygium surgery.
比较原发性翼状胬肉切除术后使用纤维蛋白组织粘合剂或10-0单尼龙缝线将结膜自体移植片附着于巩膜床的疗效。
对47例原发性鼻侧翼状胬肉患者的47只眼进行了一项比较性、前瞻性随机临床试验。第1组(粘合剂组)由21例使用纤维蛋白组织粘合剂(Quixil™)进行结膜自体移植封闭术的患者组成,第2组(缝线组)由26例在翼状胬肉切除术后使用10-0单尼龙(Ethicon(®))缝线进行翼状胬肉手术的患者组成。所有手术均由同一位外科医生进行。在术前以及术后第1、14和21天对患者进行评估。通过眼部不适问卷以及手术时间、眼部充血、并发症和复发迹象进行随访,术后第6个月也评估复发情况。数据进行统计学分析。p<0.005被认为具有统计学意义。
第1组(胶水组)平均手术时间为19.05±6.12分钟,第2组(缝线组)为48.15±7.13分钟(p<0.001)。眼部不适量表分析显示,第1组在术后第1天(p<0.005)、第7天(p<0.001)和第21天(p<0.001)得分较低。在本研究的所有时间段,第1组的眼部充血程度较轻(p<0.001)。每组各有1例并发症,两者均通过临床治疗处理至术后第21天。至术后第6个月,第1组有1例复发,第2组有2例复发。
在原发性翼状胬肉的手术治疗中,与使用10.0单尼龙缝线固定相比,纤维蛋白组织粘合剂附着结膜自体移植片可缩短手术时间,减轻结膜充血和眼部不适,术后复发情况相似,证明是原发性翼状胬肉手术中结膜自体移植片附着的极佳选择。