左炔诺孕酮宫内节育系统治疗特发性月经过多的临床疗效。
Clinical outcome of levonorgestrel intra-uterine system in idiopathic menorrhagia.
机构信息
Department of Obstetrics and Gynaecology, Lady Hardinge Medical College, New Delhi, India.
出版信息
Eur Rev Med Pharmacol Sci. 2011 Jul;15(7):764-8.
AIMS
To evaluate the efficacy, acceptability and side effects of levonorgestrel intrauterine system in patients with idiopathic menorrhagia.
METHODS
A prospective, non-randomized clinical study in which 42 women between the age of 35-55 years complaining of menorrhagia with or without irregular cycle were recruited during one year period. The women were followed up at 3, 6, 12, 24 and 36 months after insertion.
RESULTS
The reduction in mean blood loss was found to be statistically significant with a p value of < 0.001 for all the follow-up periods.
CONCLUSION
The present study projects levonorgestrel intrauterine system as an effective patient friendly device with a high degree of compliance and worth considering as a viable alternative to surgery for the management of menorrhagia due to dysfunctional uterine bleeding in developing countries like India.
目的
评估左炔诺孕酮宫内节育系统治疗特发性月经过多患者的疗效、可接受性和副作用。
方法
这是一项前瞻性、非随机的临床研究，在一年的时间里，招募了 42 名年龄在 35-55 岁之间、有或无不规则周期月经过多的女性。在放置后的 3、6、12、24 和 36 个月对这些女性进行随访。
结果
所有随访期间，平均出血量的减少均具有统计学意义（p 值均 < 0.001）。
结论
本研究表明，左炔诺孕酮宫内节育系统是一种有效的、患者友好的装置，具有高度的依从性，值得考虑作为一种可行的替代手术的方法，用于治疗发展中国家（如印度）因功能失调性子宫出血引起的月经过多。
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