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肌肉骨骼疾病负担及其与城市性、社会经济地位、年龄和性别的关系:来自 14507 名受试者的结果。

Burden of musculoskeletal disease and its determination by urbanicity, socioeconomic status, age, and sex: Results from 14,507 subjects.

机构信息

Children's Hospital Boston, Harvard Medical School, Boston, Massachusetts 02115, USA.

出版信息

Arthritis Care Res (Hoboken). 2011 Nov;63(11):1558-64. doi: 10.1002/acr.20558.

DOI:10.1002/acr.20558
PMID:21793230
Abstract

OBJECTIVE

The availability of reliable estimates of the burden of musculoskeletal disease is of considerable importance for policymakers.

METHODS

This study uses data from the 14,507 participants of the European Health Interview Survey conducted in Austria in 2006/2007 to calculate estimates of the prevalence of osteoarthritis, spinal conditions, and osteoporosis in a population representative of other European Union or Organisation for Economic Co-operation and Development member states. Urbanicity, socioeconomic status, and age and sex were included as determinants of musculoskeletal disease.

RESULTS

The prevalence of arthritis was 18.8% (95% confidence interval [95% CI] 18.2-19.4%), of spinal conditions was 38.4% (95% CI 37.6-39.2%), and of osteoporosis was 6.6% (95% CI 6.3-7.0%). The census data showed strong evidence for an association between urbanicity and arthritis (P = 0.012) and osteoporosis (P < 0.001), but not spinal conditions (P = 0.721). Arthritis and spinal conditions were associated with socioeconomic status (P < 0.001 for all). Osteoporosis showed the same associations with age, income, and education. For arthritis, a combined model showed a substantial attenuation of the effect of urbanicity on arthritis prevalence after adjustment for socioeconomic status.

CONCLUSION

These data suggest that the burden of musculoskeletal disease is determined by both urbanicity and socioeconomic status; however, the effect of urbanicity seems to be attributable to differences in socioeconomic status and demographics across geographic regions.

摘要

目的

可靠估计肌肉骨骼疾病负担对于政策制定者具有重要意义。

方法

本研究利用 2006/2007 年在奥地利进行的欧洲健康访谈调查的 14507 名参与者的数据,计算出在其他欧盟或经济合作与发展组织成员国中具有代表性的人群中骨关节炎、脊柱疾病和骨质疏松症的患病率。城市性、社会经济地位以及年龄和性别被纳入肌肉骨骼疾病的决定因素。

结果

关节炎的患病率为 18.8%(95%置信区间[95%CI] 18.2-19.4%),脊柱疾病的患病率为 38.4%(95%CI 37.6-39.2%),骨质疏松症的患病率为 6.6%(95%CI 6.3-7.0%)。人口普查数据显示,城市性与关节炎(P=0.012)和骨质疏松症(P<0.001)之间存在很强的关联证据,但与脊柱疾病(P=0.721)无关。关节炎和脊柱疾病与社会经济地位相关(所有 P<0.001)。骨质疏松症与年龄、收入和教育也存在相同的关联。对于关节炎,综合模型显示,在调整社会经济地位后,城市性对关节炎患病率的影响明显减弱。

结论

这些数据表明,肌肉骨骼疾病的负担既由城市性又由社会经济地位决定;然而,城市性的影响似乎归因于地理区域之间社会经济地位和人口统计学的差异。

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