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西洋参不能改善多发性硬化症的疲劳:一项单中心随机双盲安慰剂对照交叉先导研究。

American ginseng does not improve fatigue in multiple sclerosis: a single center randomized double-blind placebo-controlled crossover pilot study.

机构信息

Neurology Service and MS Center of Excellence-West, Portland VA Medical Center, Portland, OR, USA.

出版信息

Mult Scler. 2011 Dec;17(12):1523-6. doi: 10.1177/1352458511412062. Epub 2011 Jul 29.

DOI:10.1177/1352458511412062
PMID:21803872
Abstract

This study examined the safety and efficacy of an escalating dose (100 mg, 200 mg, 400 mg/day) of American ginseng over 6 weeks in a single-center, randomized, double-blind, placebo-controlled, crossover trial with 56 subjects with multiple sclerosis and fatigue. There were no serious adverse events but fatigue on ginseng, as assessed by the Fatigue Severity Scale, was not significantly different from fatigue on placebo.

摘要

本研究在一家单中心、随机、双盲、安慰剂对照、交叉试验中,评估了为期 6 周的递增剂量(100mg、200mg、400mg/天)西洋参对 56 例多发性硬化症和疲劳患者的安全性和疗效。没有严重不良事件,但使用疲劳严重程度量表评估的人参疲劳与安慰剂疲劳无显著差异。

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