Yamagishi Hidetsugu, Fukui Hirokazu, Tomita Shigeki, Ichikawa Kazuhito, Imura Johji, Ishizuka Mitsuru, Kubota Keiichi, Fujimori Takahiro
Department of Surgical and Molecular Pathology, Dokkyo University School of Medicine, Japan.
Intern Med. 2011;50(15):1587-9. doi: 10.2169/internalmedicine.50.5252. Epub 2011 Aug 1.
A 68-year-old woman with fecal occult blood was referred to Dokkyo Medical School Hospital. Colonoscopy demonstrated a flat lesion in the rectum, and endoscopic mucosal resection of the lesion was performed. Histologic examination revealed that it contained ectopic gastric mucosa, which had a gastric foveolar and glandular mucinous phenotype, as demonstrated by immunohistochemistry. Moreover, the lesion also contained CA19-9- and CK7-positive pancreatic duct-like components in the submucosal layer. The present case is the first report to describe ectopic gastric mucosa and pancreatic ducts concurrently arising in the rectum.
一名68岁粪便潜血的女性被转诊至独协医科大学医院。结肠镜检查发现直肠有一扁平病变,并对该病变进行了内镜黏膜切除术。组织学检查显示其含有异位胃黏膜,免疫组织化学显示其具有胃小凹和腺黏液表型。此外,该病变在黏膜下层还含有CA19-9和CK7阳性的胰管样成分。本病例是首例描述直肠同时出现异位胃黏膜和胰管的报告。