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非接触式方法用于评估皮肤机械性能,以评估衰老的影响。

Non contact method for in vivo assessment of skin mechanical properties for assessing effect of ageing.

机构信息

Laboratoire Peritesco, 75001 Paris, France.

出版信息

Med Eng Phys. 2012 Mar;34(2):172-8. doi: 10.1016/j.medengphy.2011.07.007. Epub 2011 Jul 31.

Abstract

The assessment of human tissue properties by objective and quantitative devices is very important to improve the understanding of its mechanical behaviour. The aim of this paper is to present a non contact method to measure the mechanical properties of human skin in vivo. A complete non contact device using an air flow system has been developed. Validation and assessment of the method have been performed on inert visco-elastic material. An in vivo study on the forearm of two groups of healthy women aged of 23.2±1.6 and 60.4±2.4 has been performed. Main parameters assessed are presented and a first interpretation to evaluate the reduced Young's modulus is proposed. Significant differences between the main parameters of the curve are shown with ageing. As tests were performed with different loads, the influence of the stress is also observed. We found a reduced Young's modulus with an air flow force of 10 mN of 14.38±3.61 kPa for the youngest group and 6.20±1.45 kPa for the oldest group. These values agree with other studies using classical or dynamic indentation. Non contact test using the developed device gives convincing results.

摘要

客观和定量的设备对人体组织性能的评估对于提高对其力学行为的理解非常重要。本文的目的是介绍一种非接触方法来测量人体皮肤的机械性能。已经开发了一种完整的非接触设备,该设备使用气流系统。该方法的验证和评估已在惰性粘弹性材料上进行。对年龄分别为 23.2±1.6 和 60.4±2.4 的两组健康女性的前臂进行了体内研究。评估了主要参数,并提出了一种评估降低的杨氏模量的初步解释。随着年龄的增长,曲线的主要参数显示出明显的差异。由于测试是在不同的负载下进行的,因此还观察到了应力的影响。我们发现,对于年轻组,气流力为 10 mN 时的杨氏模量降低为 14.38±3.61 kPa,而对于最年长组,杨氏模量降低为 6.20±1.45 kPa。这些值与使用经典或动态压痕的其他研究结果一致。使用所开发设备进行的非接触测试给出了令人信服的结果。

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