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[躯干硬皮病的不寻常表现]

[Unusual manifestation of scleroderma of the trunk].

作者信息

Hackel H, Zillikens D, Lechner W, Burg G

机构信息

Dermatologische Klinik, Julius-Maximilians-Universität Würzburg.

出版信息

Hautarzt. 1990 Feb;41(2):91-3.

PMID:2180858
Abstract

We present the case of an 81-year-old women with progressive systemic scleroderma. In addition to the typical manifestations of diffuse (truncal) scleroderma, including involvement of the esophagus, lungs and muscles, there were two unusual findings: large, non-sclerosing areas on the trunk simulating the disabling type of circumscribed scleroderma and high titers of anticentromere antibodies, while there were no anti-Scl-70 antibodies. The disease responded to treatment with griseofulvin.

摘要

我们报告一例81岁患有进行性系统性硬化症的女性病例。除了弥漫性(躯干型)硬皮病的典型表现,包括食管、肺和肌肉受累外,还有两个不寻常的发现:躯干上有大片非硬化区域,类似局限性硬皮病的致残类型,以及抗着丝点抗体滴度高,而无抗Scl - 70抗体。该疾病对灰黄霉素治疗有反应。

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