Department of Internal Medicine, Research Center for Pulmonary Disorders, Chonbuk National University Medical School, Jeonju, South Korea.
Lung. 2011 Oct;189(5):433-5. doi: 10.1007/s00408-011-9314-3. Epub 2011 Aug 2.
Inflammatory myofibroblastic tumor (IMT) is a rare tumorous lesion that presents as a solitary nodule. Complete surgical resection is the standard treatment. However, due to its rarity, the optimal therapeutic strategy for multiple IMTs has not been defined. A 32-year-old man was referred to our hospital for evaluation of multiple pulmonary nodules. On computed tomography (CT) scan of the chest, there were a 3.0 × 1.7 cm mass with heterogeneous enhancement in the left upper lobe and multiple small nodules bilaterally. We performed wedge resection of the mass, and histopathology revealed IMT. He was treated with oral corticosteroids. The clinical and radiologic responses were so excellent that a CT scan showed complete resolution 1 month after the initiation of corticosteroid therapy. These observations suggest that corticosteroids may be the way to treat bilateral multiple IMT of the lung.
炎性肌纤维母细胞瘤(IMT)是一种罕见的肿瘤性病变,表现为孤立性结节。完全手术切除是标准治疗方法。然而,由于其罕见性,多发性 IMT 的最佳治疗策略尚未确定。一名 32 岁男性因多发性肺结节就诊于我院。胸部 CT 扫描显示左肺上叶有一个 3.0×1.7cm 的肿块,呈不均匀增强,双侧有多个小结节。我们行肿块楔形切除术,组织病理学显示为 IMT。他接受了口服皮质类固醇治疗。临床和影像学反应非常好,皮质类固醇治疗 1 个月后 CT 扫描显示完全缓解。这些观察结果表明,皮质类固醇可能是治疗肺部双侧多发性 IMT 的方法。