从墨西哥急性中耳炎患儿中耳分离的肺炎链球菌血清型。
Streptococcus pneumoniae serotypes isolated from the middle ear of Mexican children diagnosed with acute otitis media.
机构信息
Hospital Infantil de México Federico Gómez, México, DF, México.
出版信息
Salud Publica Mex. 2011 May-Jun;53(3):207-11.
OBJECTIVE
The aim of this study was to identify the etiology and the serotypes of S. pneumoniae (Sp) in Mexican children with acute otitis media (AOM).
MATERIALS AND METHODS
The study includessamples frompatientsdiagnosed with AOM at the Federico Gomez Children's Hospital of Mexico (2002-2003),with positive culture for Sp bacteriologically confirmed in middle ear fluid obtained by tympanocentesis. All Sp were serotyped. A total of 138 samples from 135 children with AOM were included.
RESULTS
Sp was isolated in 72 samples from 70 children. Sixty (85.7%) were previously healthy and 10 (14.3%) were immunocompromised. The most common serotypes were 6B and 19F (16.67%), and 6 A, 14 and 23F (15.27%).
CONCLUSION
The distribution of serotypes among the children with AOM in the study is similar to that reported in developing cities, and 63.9% of the isolated serotypes are found to be included in the 7-Valent Pneumococcal Conjugate Vaccine (PCV), 68.1% in the 10-Valent PCV and 83.3% in 13-Valent PCV.
目的
本研究旨在确定墨西哥急性中耳炎（AOM）患儿中肺炎链球菌（Sp）的病因和血清型。
材料和方法
本研究纳入了 2002 年至 2003 年在墨西哥 Federico Gomez 儿童医院诊断为 AOM 的患者的样本，这些患者通过鼓膜切开术从中耳液中分离出 Sp 并经细菌培养阳性。对所有 Sp 进行了血清型鉴定。共纳入了 135 例 AOM 患儿的 138 份样本。
结果
从 70 名患儿的 72 份样本中分离出 Sp。其中 60 例（85.7%）既往健康，10 例（14.3%）免疫功能低下。最常见的血清型为 6B 和 19F（16.67%），以及 6A、14 和 23F（15.27%）。
结论
本研究中 AOM 患儿的血清型分布与发展中城市的报告相似，所分离的血清型中有 63.9%包含在 7 价肺炎球菌结合疫苗（PCV）中，68.1%包含在 10 价 PCV 中，83.3%包含在 13 价 PCV 中。
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