Department of Neurosurgery, Keio University School of Medicine, 35 Shinano-machi, Shinjuku-ku, Tokyo, 160-8582, Japan.
Brain Tumor Pathol. 2012 Jan;29(1):43-6. doi: 10.1007/s10014-011-0060-2. Epub 2011 Aug 12.
Intratumoral hemorrhage of hypoglossal schwannoma is very rare. A 37-year-old man was admitted to our hospital with severe headache and gait disturbance. Radiologic examination revealed subarachnoid hemorrhage and a well-circumscribed enhanced lesion compressing the medulla oblongata. Gross total removal of the intracranial tumor was performed. Histopathological examination revealed the characteristic features of a schwannoma. The tumor had several hemorrhagic areas and numerous hyalinized blood vessels. Although the mechanism of hemorrhage from schwannomas is unclear, it is hypothesized that tumor vessels showing focal sinusoidal dilatation and hyaline thickening of the walls lead to spontaneous thrombosis with consequent necrosis, and often hemorrhage.
舌下神经鞘瘤瘤内出血非常罕见。一名 37 岁男性因严重头痛和步态障碍入院。影像学检查显示蛛网膜下腔出血和边界清楚的增强病变压迫延髓。行颅内肿瘤全切除。组织病理学检查显示典型的神经鞘瘤特征。肿瘤有几个出血区和许多玻璃样血管。尽管神经鞘瘤出血的机制尚不清楚,但据推测,表现为局灶性窦状扩张和血管壁玻璃样增厚的肿瘤血管导致自发性血栓形成,继而发生坏死,常导致出血。