Barwad Adarsh, Khandelwal Niranjan, Vyas Sameer, Gogoi Dhrubajyoti, Dey Pranab
Department of Cytology, PGIMER, Chandigarh, India.
Diagn Cytopathol. 2011 Sep;39(9):700-2. doi: 10.1002/dc.21539. Epub 2010 Nov 15.
Prostate leiomyosarcoma is an extremely rare and highly aggressive neoplasm that accounts for less than 0.1% of primary prostate malignancies. Herein, we present a patient with primary leiomyosarcoma of the prostate with lung metastasis diagnosed primarily on fine-needle aspiration cytology. Characteristic cytological features such as small fascicles of spindle cells with blunt-ended nuclei, positivity for desmin and smooth muscle actin along with the radiological features are helpful in the correct diagnosis.
前列腺平滑肌肉瘤是一种极其罕见且具有高度侵袭性的肿瘤,占原发性前列腺恶性肿瘤的比例不到0.1%。在此,我们报告一例经细针穿刺细胞学检查初步诊断为原发性前列腺平滑肌肉瘤伴肺转移的患者。特征性的细胞学表现,如核钝圆的梭形细胞小束状排列、结蛋白和平滑肌肌动蛋白阳性,以及影像学特征,有助于做出正确诊断。