Huang Jian-lin, Qiu Min, Ma Lu-lin, Huang Yi, Hou Xiao-fei, Tian Xiao-jun
Department of Urology, Peking University Third Hospital, Beijing 100191, China.
Beijing Da Xue Xue Bao Yi Xue Ban. 2011 Aug 18;43(4):544-7.
To evaluate operation process and perioperative complications of patients who underwent laparoscopic radical cystectomy (LRC).
The clinical data of 49 cases of LRC from October 2004 to June 2010 were reviewed retrospectively. Perioperative complications and mortality were analyzed, and so were the operative time, blood loss and postoperative hospital stay. Perioperative complications were defined as any adverse event within 30 days of surgery. All complications were graded according to an established five-grade modification of the original Clavien system.
The mean operation time was 418 minutes, the mean blood loss was 514 mL, the transfusion rate was 36.7%, the mean transfusion volume was 578 mL, and the average postoperative hospital stay was 20 d. For urinary diversion, ileal conduits were constructed in 27 patients (55.1%), ileal neobladders in 16 patients (32.7%), and ureterocutaneostomies in 6 patients (12.2%). A total of 17 patients (34.7%) developed at least one perioperative complication. Complications of grades 1-2 occurred in 12 patients (24.5%), which included subileus, urinary tract infections, deep venous thrombosis of the lower limbs, pneumonia, etc. Complications of grades 3-5 occurred in 5 patients(10.2%), and one patient died of pulmonary embolism. Ileal neobladders and ileal conduits were similar at the operation time, blood loss, transfusion rates, postoperative hospital stay and morbidity of perioperative complications.
Morbidity of perioperative complications following LRC was still high. The most frequent complications were subileus and urinary tract infections. The surgery should be performed on selected patients, and measures need to be taken to prevent these complications. Compared with ileal conduits, ileal neobladders did not increase the operation time, blood loss and morbidity.
评估接受腹腔镜根治性膀胱切除术(LRC)患者的手术过程及围手术期并发症。
回顾性分析2004年10月至2010年6月期间49例行LRC患者的临床资料。分析围手术期并发症及死亡率,以及手术时间、失血量和术后住院时间。围手术期并发症定义为术后30天内发生的任何不良事件。所有并发症均根据既定的对原始Clavien系统的五级改良进行分级。
平均手术时间为418分钟,平均失血量为514毫升,输血率为36.7%,平均输血量为578毫升,术后平均住院时间为20天。对于尿流改道,27例患者(55.1%)构建了回肠导管,16例患者(32.7%)构建了回肠新膀胱,6例患者(12.2%)构建了输尿管皮肤造口术。共有17例患者(34.7%)发生至少一种围手术期并发症。1 - 2级并发症发生在12例患者(24.5%)中,包括小肠梗阻、尿路感染、下肢深静脉血栓形成、肺炎等。3 - 5级并发症发生在5例患者(10.2%)中,1例患者死于肺栓塞。回肠新膀胱和回肠导管在手术时间、失血量、输血率、术后住院时间和围手术期并发症发生率方面相似。
LRC术后围手术期并发症发生率仍然较高。最常见的并发症是小肠梗阻和尿路感染。手术应在选定的患者中进行,并需要采取措施预防这些并发症。与回肠导管相比,回肠新膀胱并未增加手术时间、失血量和并发症发生率。