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国际妊娠糖尿病研究协会诊断标准对墨西哥城市女性妊娠期糖尿病患病率的影响:一项横断面研究。

Effect of the diagnostic criteria of the International Association of Diabetes and Pregnancy Study Groups on the prevalence of gestational diabetes mellitus in urban Mexican women: a cross-sectional study.

机构信息

Department of Endocrinology, Instituto Nacional de Perinatología Isidro Espinosa de los Reyes, México City, México.

出版信息

Endocr Pract. 2012 Mar-Apr;18(2):146-51. doi: 10.4158/EP11167.OR.

Abstract

OBJECTIVE

To explore the prevalence of gestational diabetes mellitus (GDM), defined by the previous criteria of the American Diabetes Association (ADA), as well as the criteria suggested by the International Association of Diabetes and Pregnancy Study Groups (IADPSG), in an unselected group of urban Mexican pregnant women and to analyze the frequency of large for gestational age (LGA) newborns in this same group of women with use of both diagnostic criteria.

METHODS

A cross-sectional study included 803 consecutive Mexican urban women with a singleton pregnancy, without concomitant diseases and no prior history of GDM, who underwent a 2-step screening protocol for diagnosis of GDM at admission to prenatal care.

RESULTS

The ADA criteria identified 83 women (10.3%) whereas the IADPSG criteria diagnosed 242 women (30.1%) having GDM (P = .0001). Fasting glucose concentrations during the 100-g 3-hour oral glucose tolerance test were abnormal in 116 women (14.4%) and in 160 women (19.9%) on the basis of ADA and IADPSG criteria, respectively (P = .004). The frequency of LGA newborns was 7.4% based on IADPSG criteria and 6.0% based on ADA criteria-no significant difference (P = .64).

CONCLUSION

With use of the IADPSG criteria, the prevalence of GDM increased almost 3-fold in comparison with that for the ADA criteria. Nevertheless, no significant difference was found in the prevalence of LGA newborns.

摘要

目的

探讨在未经选择的墨西哥城市孕妇人群中,按照美国糖尿病协会(ADA)之前的标准和国际妊娠糖尿病研究组(IADPSG)建议的标准,妊娠期糖尿病(GDM)的患病率,并分析在该人群中使用这两种诊断标准时,巨大儿(LGA)新生儿的发生率。

方法

一项横断面研究纳入了 803 例连续的墨西哥城市单胎妊娠孕妇,无合并症且无 GDM 病史,她们在产前保健就诊时接受了两步筛查方案以诊断 GDM。

结果

ADA 标准诊断出 83 例(10.3%),而 IADPSG 标准诊断出 242 例(30.1%)患有 GDM(P =.0001)。在 100g 3 小时口服葡萄糖耐量试验中,116 例(14.4%)和 160 例(19.9%)妇女的空腹血糖浓度异常,分别基于 ADA 和 IADPSG 标准(P =.004)。根据 IADPSG 标准,LGA 新生儿的发生率为 7.4%,根据 ADA 标准为 6.0%,差异无统计学意义(P =.64)。

结论

与 ADA 标准相比,使用 IADPSG 标准,GDM 的患病率增加了近 3 倍。然而,LGA 新生儿的患病率没有显著差异。

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