慢性血液透析患者的冷球蛋白血症。
Cryoglobulinemia in chronic hemodialysis patients.
机构信息
Santa Casa Medical School and Hospital, São Paulo, Brazil.
出版信息
Ren Fail. 2011;33(8):801-4. doi: 10.3109/0886022X.2011.601828.
BACKGROUND
Renal failure patients submitted to chronic hemodialysis can present with cryoglobulinemia. There are few studies on cryoglobulins in chronic hemodialysis patients. The aim of the present study was to determine the prevalence and to identify the components of cryoglobulins in chronic hemodialysis patients.
METHODS
Fifty-four patients on chronic hemodialysis were evaluated for the presence of cryoglobulins, after inclusion and exclusion criteria. The components of the cryoprecipitate were analyzed.
RESULTS
Cryoglobulins were detected in 83% (45/54) of the patients on chronic hemodialysis. The cryoprecipitate was constituted by IgG, IgM, IgA, and complement fractions C3 and C4.
CONCLUSION
We concluded that there was a high prevalence of cryoglobulins in chronic hemodialysis patients, and the cryoprecipitate was constituted by IgG, IgM, IgA, and complement fractions C3 and C4.
背景
接受慢性血液透析的肾衰竭患者可能会出现冷球蛋白血症。关于慢性血液透析患者冷球蛋白的研究较少。本研究旨在确定慢性血液透析患者冷球蛋白的患病率，并确定其成分。
方法
在纳入和排除标准后，对 54 名慢性血液透析患者进行冷球蛋白检测。分析冷沉淀的成分。
结果
在 83%（45/54）的慢性血液透析患者中检测到冷球蛋白。冷沉淀由 IgG、IgM、IgA 和补体 C3 和 C4 组成。
结论
我们得出结论，慢性血液透析患者冷球蛋白的患病率较高，冷沉淀由 IgG、IgM、IgA 和补体 C3 和 C4 组成。
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