Dipartimento di Medicina Sperimentale, II Università di Napoli, 80138 Naples, Italy.
Mini Rev Med Chem. 2011 Oct;11(12):1075-81. doi: 10.2174/138955711797247770.
In the last years novel therapeutic approaches for the treatment of cancer have been proposed: specific inhibitors of serine/threonine and tyrosine kinases, angiogenesis inhibitors, antibodies against receptors/surface molecules on cancer cells, gene therapy approaches and others. In a lot of cases the clinical trials have confirmed the efficacy of these approaches. Here, we will review the discovered new potential molecular targets for the treatment of human testicular seminomas.
在过去的几年中,已经提出了治疗癌症的新的治疗方法:丝氨酸/苏氨酸和酪氨酸激酶的特异性抑制剂、血管生成抑制剂、针对癌细胞表面受体/分子的抗体、基因治疗方法等。在许多情况下,临床试验已经证实了这些方法的疗效。在这里,我们将回顾发现的治疗人类睾丸精原细胞瘤的新的潜在分子靶点。